Maternal recognition of pregnancy in the rabbit

R. A. Nowak, J. M. Bahr

Research output: Contribution to journalArticlepeer-review


Conceptuses were removed by extrusion through incisions in the uterus on Days 11, 12 and 18 post coitum (p.c.). Pseudopregnant does at Days 11 and 12 and pregnant does at Day 18 were sham-operated and served as controls. Blood samples were collected before and daily for 3 days after conceptus removal. Serum progesterone profiles of does whose conceptuses were removed on Day 11 p.c. were identical to those of intact pseudopregnant and sham-operated pseudopregnant controls. Conceptus removal on Days 12 or 18 p.c. resulted in a precipitous decline (P < 0.01) in progesterone levels within 48 h. LH levels were low (<1 ng/ml) in all groups before and after surgery and there were no significant differences between treated and control rabbits. These data demonstrate that the maternal recognition of pregnancy occurs by Day 12 of gestation and that conceptus removal does not result in an alteration in serum LH levels.

Original languageEnglish (US)
Pages (from-to)623-627
Number of pages5
JournalJournal of Reproduction and Fertility
Issue number2
StatePublished - 1983

ASJC Scopus subject areas

  • Physiology
  • Embryology
  • Molecular Biology
  • Obstetrics and Gynecology
  • Developmental Biology


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