TY - JOUR
T1 - Manic symptoms and quality of life in bipolar disorder
AU - Gazalle, Fernando Kratz
AU - Hallal, Pedro Curi
AU - Andreazza, Ana Cristina
AU - Frey, Benício Noronha
AU - Kauer-Sant'Anna, Márcia
AU - Weyne, Fernanda
AU - da Costa, Sabrina Corrêa
AU - Santin, Aida
AU - Kapczinski, Flávio
N1 - Funding Information:
This work was supported by grants from CNPq–Brazil, CAPES–Brazil, FIPE (HCPA)–Brazil.
PY - 2007/9/30
Y1 - 2007/9/30
N2 - This study evaluates the influence of manic symptoms on quality of life in a sample of adult bipolar disorder (BD) patients. This was a cross-sectional study including 125 BD outpatients from a university-based program. All patients were diagnosed using the Structured Clinical Interview for DSM-IV for BD. Manic symptoms and quality of life were assessed using the Young Mania Rating Scale (YMRS) and the World Health Organization Quality of Life Instrument-Short Version (WHOQOL-BREF), respectively. In the unadjusted analysis using linear regression, the score of manic symptoms was inversely associated with scores of quality of life within the social domain of the WHOQOL. In the adjusted analysis, the score of manic symptoms was inversely associated with the social, physical, and psychological domains of the WHOQOL. In a separate analysis at the YMRS items, items 4 (irritability) and 5 (sleep) were associated with lower quality of life.
AB - This study evaluates the influence of manic symptoms on quality of life in a sample of adult bipolar disorder (BD) patients. This was a cross-sectional study including 125 BD outpatients from a university-based program. All patients were diagnosed using the Structured Clinical Interview for DSM-IV for BD. Manic symptoms and quality of life were assessed using the Young Mania Rating Scale (YMRS) and the World Health Organization Quality of Life Instrument-Short Version (WHOQOL-BREF), respectively. In the unadjusted analysis using linear regression, the score of manic symptoms was inversely associated with scores of quality of life within the social domain of the WHOQOL. In the adjusted analysis, the score of manic symptoms was inversely associated with the social, physical, and psychological domains of the WHOQOL. In a separate analysis at the YMRS items, items 4 (irritability) and 5 (sleep) were associated with lower quality of life.
KW - Bipolar disorder
KW - Depressed mood
KW - Manic symptoms
KW - Quality of life
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U2 - 10.1016/j.psychres.2006.07.007
DO - 10.1016/j.psychres.2006.07.007
M3 - Article
C2 - 17544154
AN - SCOPUS:34548474260
SN - 0165-1781
VL - 153
SP - 33
EP - 38
JO - Psychiatry Research
JF - Psychiatry Research
IS - 1
ER -