TY - JOUR
T1 - Managing Hyperkalemia
T2 - Another Benefit of Exercise in People With Chronic Kidney Disease?
AU - St-Jules, David E.
AU - Marinaro, Meredith
AU - Goldfarb, David S.
AU - Byham-Gray, Laura D.
AU - Wilund, Kenneth R.
N1 - Funding Information:
Financial Disclosure: D.E.S and D.S.G. are investigators on an Investigator-Sponsored Trial from Relypsa, Inc. (ClinicalTrials.gov Identifier: NCT03183778). M.M. is a full time employee of Akebia Therapeutics.
Publisher Copyright:
© 2019 National Kidney Foundation, Inc.
PY - 2020/9
Y1 - 2020/9
N2 - People with chronic kidney disease (CKD) are at increased risk of hyperkalemia, an electrolyte abnormality that can cause serious, sometimes fatal, cardiac arrhythmias. Muscle contraction causes potassium to be released from cells, increasing serum potassium concentrations. However, these effects are transient, and the long-term impact of exercise training on hyperkalemia risk in CKD patients is largely unknown. In this review, we examine the effects of exercise on factors affecting potassium balance in people with CKD, highlighting the potential benefits of regular exercise on hyperkalemia risk in this population. Although regular exercise is already recommended for people with CKD, research examining this hypothesis may lead to novel therapeutic treatments for this life-threatening condition.
AB - People with chronic kidney disease (CKD) are at increased risk of hyperkalemia, an electrolyte abnormality that can cause serious, sometimes fatal, cardiac arrhythmias. Muscle contraction causes potassium to be released from cells, increasing serum potassium concentrations. However, these effects are transient, and the long-term impact of exercise training on hyperkalemia risk in CKD patients is largely unknown. In this review, we examine the effects of exercise on factors affecting potassium balance in people with CKD, highlighting the potential benefits of regular exercise on hyperkalemia risk in this population. Although regular exercise is already recommended for people with CKD, research examining this hypothesis may lead to novel therapeutic treatments for this life-threatening condition.
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U2 - 10.1053/j.jrn.2019.10.001
DO - 10.1053/j.jrn.2019.10.001
M3 - Review article
C2 - 31767517
AN - SCOPUS:85076521467
SN - 1051-2276
VL - 30
SP - 380
EP - 383
JO - Journal of Renal Nutrition
JF - Journal of Renal Nutrition
IS - 5
ER -