TY - GEN
T1 - Magnetic Resonance Imaging (MRI) of water diffusion in 2-Hydroxyethyl Methacrylate (HEMA) gels
AU - Raguin, Guy
AU - Falkenberg, Cibele V.
AU - Prakash, Shaurya
AU - FitzHenry, Heather R.
AU - Mensing, Glennys
AU - Ciobanu, Luisa
AU - Georgiadis, John G.
AU - Shannon, Mark A.
PY - 2006
Y1 - 2006
N2 - A fundamental study focusing on correlating the local water self-diffusion coefficient to the local free water content in 2-hydroxyethyl methacrylate (HEMA) gels was conducted. HEMA gels were synthesized with different nominal water content (50% to 90%). MRI measurements of local diffusion coefficient distribution and local water content profiles were conducted on a 600 MHz scanner. The local water content was measured via two spin-echo images with sufficiently long repetition time (TR) to eliminate T1-weighting and two values for the echo time (TE) in order to account for T2-weighting. The local diffusion coefficient was determined using a standard pulsed-field gradient spin-echo sequence. The measured local water content and diffusion coefficient data were compared with several single-parameter diffusion models for interstitial diffusion in the hydrogel (Makie-Meares, Stokes-Einstein, and Brownian motion around overlapping spheres).
AB - A fundamental study focusing on correlating the local water self-diffusion coefficient to the local free water content in 2-hydroxyethyl methacrylate (HEMA) gels was conducted. HEMA gels were synthesized with different nominal water content (50% to 90%). MRI measurements of local diffusion coefficient distribution and local water content profiles were conducted on a 600 MHz scanner. The local water content was measured via two spin-echo images with sufficiently long repetition time (TR) to eliminate T1-weighting and two values for the echo time (TE) in order to account for T2-weighting. The local diffusion coefficient was determined using a standard pulsed-field gradient spin-echo sequence. The measured local water content and diffusion coefficient data were compared with several single-parameter diffusion models for interstitial diffusion in the hydrogel (Makie-Meares, Stokes-Einstein, and Brownian motion around overlapping spheres).
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U2 - 10.1557/proc-0930-jj04-05
DO - 10.1557/proc-0930-jj04-05
M3 - Conference contribution
AN - SCOPUS:33947674332
SN - 155899887X
SN - 9781558998872
T3 - Materials Research Society Symposium Proceedings
SP - 47
EP - 52
BT - Materials Science of Water Purification
PB - Materials Research Society
T2 - 2006 MRS Spring Meeting
Y2 - 17 April 2006 through 21 April 2006
ER -