Magnetic resonance imaging in canine idiopathic epilepsy: a mini-review

Kari D. Foss, Audrey C. Billhymer

Research output: Contribution to journalShort surveypeer-review

Abstract

Magnetic resonance imaging (MRI) in an integral part of the diagnostic workup in canines with idiopathic epilepsy (IE). While highly sensitive and specific in identifying structural lesions, conventional MRI is unable to detect changes at the microscopic level. Utilizing more advanced neuroimaging techniques may provide further information on changes at the neuronal level in the brain of canines with IE, thus providing crucial information on the pathogenesis of canine epilepsy. Additionally, earlier detection of these changes may aid clinicians in the development of improved and targeted therapies. Advances in MRI techniques are being developed which can assess metabolic, cellular, architectural, and functional alterations; as well alterations in neuronal tissue mechanical properties, some of which are currently being applied in research on canine IE. This mini-review focuses on novel MRI techniques being utilized to better understand canine epilepsy, which include magnetic resonance spectroscopy, diffusion-weighted imaging, diffusion tensor imaging, perfusion-weighted imaging, voxel based morphometry, and functional MRI; as well as techniques applied in human medicine and their potential use in veterinary species.

Original languageEnglish (US)
Article number1427403
JournalFrontiers in Veterinary Science
Volume11
DOIs
StatePublished - 2024

Keywords

  • MRI
  • brain
  • dog
  • epilepsy
  • neuroimaging
  • seizure

ASJC Scopus subject areas

  • General Veterinary

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