Pluripotent stem cells transition between distinct naive and primed states that are controlled by overlapping sets of master regulatory transcription factors. In this issue of Cell Stem Cell, Buecker et al. (2014) and Factor et al. (2014) demonstrate that alternate enhancer usage, regulated by state-specific binding partners of master regulators, defines these pluripotent state transitions.
|Original language||English (US)|
|Number of pages||2|
|Journal||Cell Stem Cell|
|State||Published - Jun 5 2014|
ASJC Scopus subject areas
- Molecular Medicine
- Cell Biology