Longitudinal association between depressive symptoms and walking impairment in people with relapsing-remitting multiple sclerosis

Ipek Ensari, Brynn C. Adamson, Robert W. Motl

Research output: Contribution to journalArticle

Abstract

Worsening depressive symptoms and walking impairment are significant burdens in multiple sclerosis. We explored the reciprocal relationship between depressive symptoms and walking impairment in a cohort of 269 people with relapsing-remitting multiple sclerosis over 2 years. The data were examined using longitudinal panel analysis in Mplus. Baseline depressive symptoms predicted change in walking impairment at 1-year follow-up (path coefficient =.074), and change in walking impairment at 1-year follow-up predicted change in depressive symptoms at 2-year follow-up (path coefficient =.177). Our study provides preliminary evidence for initiation of a reciprocal relationship between depressive symptoms and walking impairment in relapsing-remitting multiple sclerosis.

Original languageEnglish (US)
Pages (from-to)2732-2741
Number of pages10
JournalJournal of Health Psychology
Volume21
Issue number11
DOIs
StatePublished - Nov 1 2016

Keywords

  • chronic illness
  • cohort
  • depression
  • path analysis
  • physical activity

ASJC Scopus subject areas

  • Applied Psychology

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