TY - JOUR
T1 - Longitudinal analysis of differences and similarities in antimicrobial resistance among commensal Escherichia coli isolated from market swine and sows at slaughter in the United States of America, 2013–2019
AU - Sodagari, Hamid Reza
AU - Agrawal, Isha
AU - Yudhanto, Setyo
AU - Varga, Csaba
N1 - Funding Information:
We would like to thank the National Antimicrobial Resistance Monitoring System for Enteric Bacteria (NARMS) for generating the data and making it publicly available. We also express our sincere gratitude to all the veterinarians and slaughterhouse staff who actively participated in this study.
Publisher Copyright:
© 2023 Elsevier B.V.
PY - 2023/12/16
Y1 - 2023/12/16
N2 - The emergence of antimicrobial resistance in swine enteric bacteria poses a significant public health challenge. Our study evaluated publicly available data collected by the National Antimicrobial Resistance Monitoring System for Enteric Bacteria (NARMS) between 2013 and 2019 at slaughter plants across the United States of America, focusing on commensal E. coli isolated from swine cecal contents originating from two distinct swine production systems: market hogs (n = 2090) and sows (n = 1147). In both production types, the highest pairwise correlations were detected among β-lactam antimicrobials, including resistance to amoxicillin-clavulanic acid, ceftriaxone, and cefoxitin, suggesting a co-selection for resistance. Compared to 2013, an increase in the rate of E. coli isolates that were resistant to β-lactam antimicrobials was higher in 2017, 2018, and 2019, and this increase was more pronounced in isolates obtained from market hogs. Differences in antimicrobial resistance between these two distinct swine production systems warrant production-type focused mitigation efforts.
AB - The emergence of antimicrobial resistance in swine enteric bacteria poses a significant public health challenge. Our study evaluated publicly available data collected by the National Antimicrobial Resistance Monitoring System for Enteric Bacteria (NARMS) between 2013 and 2019 at slaughter plants across the United States of America, focusing on commensal E. coli isolated from swine cecal contents originating from two distinct swine production systems: market hogs (n = 2090) and sows (n = 1147). In both production types, the highest pairwise correlations were detected among β-lactam antimicrobials, including resistance to amoxicillin-clavulanic acid, ceftriaxone, and cefoxitin, suggesting a co-selection for resistance. Compared to 2013, an increase in the rate of E. coli isolates that were resistant to β-lactam antimicrobials was higher in 2017, 2018, and 2019, and this increase was more pronounced in isolates obtained from market hogs. Differences in antimicrobial resistance between these two distinct swine production systems warrant production-type focused mitigation efforts.
KW - Antimicrobial resistance
KW - Cecal samples
KW - Market hog
KW - Multidrug resistance
KW - Pigs
KW - Slaughter
KW - Sow
KW - Surveillance
KW - United States of America
UR - http://www.scopus.com/inward/record.url?scp=85170416045&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85170416045&partnerID=8YFLogxK
U2 - 10.1016/j.ijfoodmicro.2023.110388
DO - 10.1016/j.ijfoodmicro.2023.110388
M3 - Article
C2 - 37699314
AN - SCOPUS:85170416045
SN - 0168-1605
VL - 407
JO - International Journal of Food Microbiology
JF - International Journal of Food Microbiology
M1 - 110388
ER -