Long, Saturated Chains: Tasty Domains for Kinases of Insulin Resistance

Vladimir Lizunov, Petr Chlanda, Mary L Kraft, Joshua Zimmerberg

Research output: Contribution to journalShort survey

Abstract

The mechanistic basis of how cells respond to increased fatty acids (FAs) is murky but potentially involves receptor-mediated activation or inhibition by different FA classes. Holzer et al. (2011) recently propose in Cell that expansion of intracellular membrane microdomains induced by saturated FA recruit and activate c-Src for JNK activation.

Original languageEnglish (US)
Pages (from-to)604-606
Number of pages3
JournalDevelopmental cell
Volume21
Issue number4
DOIs
StatePublished - Oct 18 2011

Fingerprint

Insulin Resistance
Phosphotransferases
Fatty Acids
Insulin
Chemical activation
Membrane Microdomains
Intracellular Membranes
Membranes

ASJC Scopus subject areas

  • Developmental Biology

Cite this

Long, Saturated Chains : Tasty Domains for Kinases of Insulin Resistance. / Lizunov, Vladimir; Chlanda, Petr; Kraft, Mary L; Zimmerberg, Joshua.

In: Developmental cell, Vol. 21, No. 4, 18.10.2011, p. 604-606.

Research output: Contribution to journalShort survey

Lizunov, Vladimir ; Chlanda, Petr ; Kraft, Mary L ; Zimmerberg, Joshua. / Long, Saturated Chains : Tasty Domains for Kinases of Insulin Resistance. In: Developmental cell. 2011 ; Vol. 21, No. 4. pp. 604-606.
@article{82328e01078f4b11ba7fdb5161b4e01a,
title = "Long, Saturated Chains: Tasty Domains for Kinases of Insulin Resistance",
abstract = "The mechanistic basis of how cells respond to increased fatty acids (FAs) is murky but potentially involves receptor-mediated activation or inhibition by different FA classes. Holzer et al. (2011) recently propose in Cell that expansion of intracellular membrane microdomains induced by saturated FA recruit and activate c-Src for JNK activation.",
author = "Vladimir Lizunov and Petr Chlanda and Kraft, {Mary L} and Joshua Zimmerberg",
year = "2011",
month = "10",
day = "18",
doi = "10.1016/j.devcel.2011.10.001",
language = "English (US)",
volume = "21",
pages = "604--606",
journal = "Developmental Cell",
issn = "1534-5807",
publisher = "Cell Press",
number = "4",

}

TY - JOUR

T1 - Long, Saturated Chains

T2 - Tasty Domains for Kinases of Insulin Resistance

AU - Lizunov, Vladimir

AU - Chlanda, Petr

AU - Kraft, Mary L

AU - Zimmerberg, Joshua

PY - 2011/10/18

Y1 - 2011/10/18

N2 - The mechanistic basis of how cells respond to increased fatty acids (FAs) is murky but potentially involves receptor-mediated activation or inhibition by different FA classes. Holzer et al. (2011) recently propose in Cell that expansion of intracellular membrane microdomains induced by saturated FA recruit and activate c-Src for JNK activation.

AB - The mechanistic basis of how cells respond to increased fatty acids (FAs) is murky but potentially involves receptor-mediated activation or inhibition by different FA classes. Holzer et al. (2011) recently propose in Cell that expansion of intracellular membrane microdomains induced by saturated FA recruit and activate c-Src for JNK activation.

UR - http://www.scopus.com/inward/record.url?scp=80054732698&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=80054732698&partnerID=8YFLogxK

U2 - 10.1016/j.devcel.2011.10.001

DO - 10.1016/j.devcel.2011.10.001

M3 - Short survey

C2 - 22014518

AN - SCOPUS:80054732698

VL - 21

SP - 604

EP - 606

JO - Developmental Cell

JF - Developmental Cell

SN - 1534-5807

IS - 4

ER -