Long, Saturated Chains: Tasty Domains for Kinases of Insulin Resistance

Vladimir Lizunov, Petr Chlanda, Mary Kraft, Joshua Zimmerberg

Research output: Contribution to journalShort survey

Abstract

The mechanistic basis of how cells respond to increased fatty acids (FAs) is murky but potentially involves receptor-mediated activation or inhibition by different FA classes. Holzer et al. (2011) recently propose in Cell that expansion of intracellular membrane microdomains induced by saturated FA recruit and activate c-Src for JNK activation.

Original languageEnglish (US)
Pages (from-to)604-606
Number of pages3
JournalDevelopmental cell
Volume21
Issue number4
DOIs
StatePublished - Oct 18 2011

ASJC Scopus subject areas

  • Molecular Biology
  • Biochemistry, Genetics and Molecular Biology(all)
  • Developmental Biology
  • Cell Biology

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