@article{5a573cb5d89247fe9cfd93eca2bd9cf4,
title = "Long-Distance Cooperative and Antagonistic RNA Polymerase Dynamics via DNA Supercoiling",
abstract = "Supercoiling introduced into DNA strands during the process of transcription influences other transcribing RNA polymerases over long distances, providing a physical basis for cooperative and antagonistic polymerase group behaviors.",
keywords = "DNA supercoiling, RNA polymerase, gene regulation, group dynamics, premature termination, transcription elongation",
author = "Sangjin Kim and Bruno Beltran and Irnov Irnov and Christine Jacobs-Wagner",
note = "We thank Drs. Carol Gross, Jonathan Weissman, Matthew Larson, Hendrik Osadnik, and Jeff Hussmann for helpful discussions and technical help; Drs. Samuel Kou and Andrei Kuzminov for useful suggestions; Drs. Wayne Wade and Jeorg Bewersdorf for materials; and Dr. Andrew Goodman for allowing us to use his real-time PCR machine. We also thank Dr. Patricia Rosa and the members of the Jacobs-Wagner laboratory for discussions and critical reading of the manuscript. C.J.-W. is an Investigator of the Howard Hughes Medical Institute. S.K. and C.J.-W. designed the study. S.K. performed experiments, and S.K. B.B. and C.J.-W. analyzed and discussed the data. S.K. B.B. and. I.I. provided resources. S.K. and C.J.-W. wrote the manuscript. All authors contributed to its editing. The authors declare no competing interests.",
year = "2019",
month = sep,
day = "19",
doi = "10.1016/j.cell.2019.08.033",
language = "English (US)",
volume = "179",
pages = "106--119.e16",
journal = "Cell",
issn = "0092-8674",
publisher = "Elsevier B.V.",
number = "1",
}