Long-Distance Cooperative and Antagonistic RNA Polymerase Dynamics via DNA Supercoiling

Sangjin Kim; Bruno Beltran; Irnov Irnov; Christine Jacobs-Wagner

doi:10.1016/j.cell.2019.08.033

Long-Distance Cooperative and Antagonistic RNA Polymerase Dynamics via DNA Supercoiling

Sangjin Kim, Bruno Beltran, Irnov Irnov, Christine Jacobs-Wagner

Research output: Contribution to journal › Article › peer-review

Abstract

Supercoiling introduced into DNA strands during the process of transcription influences other transcribing RNA polymerases over long distances, providing a physical basis for cooperative and antagonistic polymerase group behaviors.

Original language	English (US)
Pages (from-to)	106-119.e16
Journal	Cell
Volume	179
Issue number	1
DOIs	https://doi.org/10.1016/j.cell.2019.08.033
State	Published - Sep 19 2019
Externally published	Yes

Keywords

DNA supercoiling
RNA polymerase
gene regulation
group dynamics
premature termination
transcription elongation

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology

Online availability

10.1016/j.cell.2019.08.033

Library availability

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title = "Long-Distance Cooperative and Antagonistic RNA Polymerase Dynamics via DNA Supercoiling",

abstract = "Supercoiling introduced into DNA strands during the process of transcription influences other transcribing RNA polymerases over long distances, providing a physical basis for cooperative and antagonistic polymerase group behaviors.",

keywords = "DNA supercoiling, RNA polymerase, gene regulation, group dynamics, premature termination, transcription elongation",

author = "Sangjin Kim and Bruno Beltran and Irnov Irnov and Christine Jacobs-Wagner",

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year = "2019",

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doi = "10.1016/j.cell.2019.08.033",

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AU - Beltran, Bruno

AU - Irnov, Irnov

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Y1 - 2019/9/19

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KW - gene regulation

KW - group dynamics

KW - premature termination

KW - transcription elongation

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Long-Distance Cooperative and Antagonistic RNA Polymerase Dynamics via DNA Supercoiling

Abstract

Keywords

ASJC Scopus subject areas

Online availability

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