Long-Distance Cooperative and Antagonistic RNA Polymerase Dynamics via DNA Supercoiling

Sangjin Kim, Bruno Beltran, Irnov Irnov, Christine Jacobs-Wagner

Research output: Contribution to journal › Article

Abstract

Supercoiling introduced into DNA strands during the process of transcription influences other transcribing RNA polymerases over long distances, providing a physical basis for cooperative and antagonistic polymerase group behaviors.

Original languageEnglish (US)
Pages (from-to)106-119.e16
JournalCell
Volume179
Issue number1
DOIs
StatePublished - Sep 19 2019

Fingerprint

DNA-Directed RNA Polymerases
Transcription
DNA

Keywords

  • DNA supercoiling
  • RNA polymerase
  • gene regulation
  • group dynamics
  • premature termination
  • transcription elongation

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Long-Distance Cooperative and Antagonistic RNA Polymerase Dynamics via DNA Supercoiling. / Kim, Sangjin; Beltran, Bruno; Irnov, Irnov; Jacobs-Wagner, Christine.

In: Cell, Vol. 179, No. 1, 19.09.2019, p. 106-119.e16.

Research output: Contribution to journal › Article

Kim, S, Beltran, B, Irnov, I & Jacobs-Wagner, C 2019, 'Long-Distance Cooperative and Antagonistic RNA Polymerase Dynamics via DNA Supercoiling', Cell, vol. 179, no. 1, pp. 106-119.e16. https://doi.org/10.1016/j.cell.2019.08.033
Kim S, Beltran B, Irnov I, Jacobs-Wagner C. Long-Distance Cooperative and Antagonistic RNA Polymerase Dynamics via DNA Supercoiling. Cell. 2019 Sep 19;179(1):106-119.e16. https://doi.org/10.1016/j.cell.2019.08.033
Kim, Sangjin ; Beltran, Bruno ; Irnov, Irnov ; Jacobs-Wagner, Christine. / Long-Distance Cooperative and Antagonistic RNA Polymerase Dynamics via DNA Supercoiling. In: Cell. 2019 ; Vol. 179, No. 1. pp. 106-119.e16.
@article{5a573cb5d89247fe9cfd93eca2bd9cf4,
title = "Long-Distance Cooperative and Antagonistic RNA Polymerase Dynamics via DNA Supercoiling",
abstract = "Supercoiling introduced into DNA strands during the process of transcription influences other transcribing RNA polymerases over long distances, providing a physical basis for cooperative and antagonistic polymerase group behaviors.",
keywords = "DNA supercoiling, RNA polymerase, gene regulation, group dynamics, premature termination, transcription elongation",
author = "Sangjin Kim and Bruno Beltran and Irnov Irnov and Christine Jacobs-Wagner",
year = "2019",
month = "9",
day = "19",
doi = "10.1016/j.cell.2019.08.033",
language = "English (US)",
volume = "179",
pages = "106--119.e16",
journal = "Cell",
issn = "0092-8674",
publisher = "Cell Press",
number = "1",

}

TY - JOUR

T1 - Long-Distance Cooperative and Antagonistic RNA Polymerase Dynamics via DNA Supercoiling

AU - Kim, Sangjin

AU - Beltran, Bruno

AU - Irnov, Irnov

AU - Jacobs-Wagner, Christine

PY - 2019/9/19

Y1 - 2019/9/19

N2 - Supercoiling introduced into DNA strands during the process of transcription influences other transcribing RNA polymerases over long distances, providing a physical basis for cooperative and antagonistic polymerase group behaviors.

AB - Supercoiling introduced into DNA strands during the process of transcription influences other transcribing RNA polymerases over long distances, providing a physical basis for cooperative and antagonistic polymerase group behaviors.

KW - DNA supercoiling

KW - RNA polymerase

KW - gene regulation

KW - group dynamics

KW - premature termination

KW - transcription elongation

UR - http://www.scopus.com/inward/record.url?scp=85071954773&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85071954773&partnerID=8YFLogxK

U2 - 10.1016/j.cell.2019.08.033

DO - 10.1016/j.cell.2019.08.033

M3 - Article

C2 - 31539491

AN - SCOPUS:85071954773

VL - 179

SP - 106-119.e16

JO - Cell

JF - Cell

SN - 0092-8674

IS - 1

ER -

Access to Document