Long-Distance Cooperative and Antagonistic RNA Polymerase Dynamics via DNA Supercoiling

Sangjin Kim, Bruno Beltran, Irnov Irnov, Christine Jacobs-Wagner

Research output: Contribution to journal › Article

Abstract

Supercoiling introduced into DNA strands during the process of transcription influences other transcribing RNA polymerases over long distances, providing a physical basis for cooperative and antagonistic polymerase group behaviors.

Original languageEnglish (US)
Pages (from-to)106-119.e16
JournalCell
Volume179
Issue number1
DOIs
StatePublished - Sep 19 2019
Externally publishedYes

Fingerprint

DNA-Directed RNA Polymerases
Transcription
DNA

Keywords

  • DNA supercoiling
  • RNA polymerase
  • gene regulation
  • group dynamics
  • premature termination
  • transcription elongation

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Long-Distance Cooperative and Antagonistic RNA Polymerase Dynamics via DNA Supercoiling. / Kim, Sangjin; Beltran, Bruno; Irnov, Irnov; Jacobs-Wagner, Christine.

In: Cell, Vol. 179, No. 1, 19.09.2019, p. 106-119.e16.

Research output: Contribution to journal › Article

Kim, S, Beltran, B, Irnov, I & Jacobs-Wagner, C 2019, 'Long-Distance Cooperative and Antagonistic RNA Polymerase Dynamics via DNA Supercoiling', Cell, vol. 179, no. 1, pp. 106-119.e16. https://doi.org/10.1016/j.cell.2019.08.033
Kim S, Beltran B, Irnov I, Jacobs-Wagner C. Long-Distance Cooperative and Antagonistic RNA Polymerase Dynamics via DNA Supercoiling. Cell. 2019 Sep 19;179(1):106-119.e16. https://doi.org/10.1016/j.cell.2019.08.033
Kim, Sangjin ; Beltran, Bruno ; Irnov, Irnov ; Jacobs-Wagner, Christine. / Long-Distance Cooperative and Antagonistic RNA Polymerase Dynamics via DNA Supercoiling. In: Cell. 2019 ; Vol. 179, No. 1. pp. 106-119.e16.
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