Localized optical activation of therapeutic gene release in breast cancer cells using photothermal nanocrescents as oligonucleotide-carriers

Eunice S. Lee, Gang Logan Liu, Franklin J. Kim, Angelee Kumar, Luke P. Lee

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Optical activation of photothermal nanoparticles permits remotely-triggered surface biomolecular reactions with high spatiotemporal resolution. We present a new method to selectively and locally control protein expression by internalizing photothermal nanocrescent particles carrying therapeutic genes within living cells.

Original languageEnglish (US)
Title of host publicationMicro Total Analysis Systems - Proceedings of MicroTAS 2006 Conference
Subtitle of host publication10th International Conference on Miniaturized Systems for Chemistry and Life Sciences
PublisherJapan Academic Association Inc
Pages284-286
Number of pages3
StatePublished - 2006
Externally publishedYes
Event10th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2006 - Tokyo, Japan
Duration: Nov 5 2006Nov 9 2006

Other

Other10th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2006
CountryJapan
CityTokyo
Period11/5/0611/9/06

Keywords

  • Gene delivery
  • Molecular nanomedicine
  • Photothermal nanoparticles

ASJC Scopus subject areas

  • Chemical Engineering (miscellaneous)
  • Bioengineering

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