"Living" microvascular stamp for patterning of functional neovessels; Orchestrated control of matrix property and geometry

Jae Hyun Jeong; Vincent Chan; Chaenyung Cha; Pinar Zorlutuna; Casey Dyck; K Jimmy Hsia; Rashid Bashir; Hyunjoon Kong

doi:10.1002/adma.201103207

"Living" microvascular stamp for patterning of functional neovessels; Orchestrated control of matrix property and geometry

Jae Hyun Jeong, Vincent Chan, Chaenyung Cha, Pinar Zorlutuna, Casey Dyck, K Jimmy Hsia, Rashid Bashir, Hyunjoon Kong

Research output: Contribution to journal › Article › peer-review

Abstract

This study presents a "living" microvascular stamp that releases multiple angiogenic factors and subsequently creates functional neovessels with the same pattern as that engraved in the stamp. The stamp consists of live cells that secrete angiogenic factors, an engineered hydrogel matrix that promotes cellular expression of angiogenic factors, and a three-dimensional geometry that localizes the angiogenic factors within the pattern.

Original language	English (US)
Pages (from-to)	58-63
Number of pages	6
Journal	Advanced Materials
Volume	24
Issue number	1
DOIs	https://doi.org/10.1002/adma.201103207
State	Published - Jan 3 2012

Keywords

angiogenesis
cell-encapsulation
methacrylic alginate
patterned neovessels
stereolithography

ASJC Scopus subject areas

General Materials Science
Mechanics of Materials
Mechanical Engineering

Online availability

10.1002/adma.201103207

Library availability

Discover UIUC Full Text

Cite this

@article{7261ae73c40c4d4b96dbc0bbe1f9c2a3,

title = "{"}Living{"} microvascular stamp for patterning of functional neovessels; Orchestrated control of matrix property and geometry",

abstract = "This study presents a {"}living{"} microvascular stamp that releases multiple angiogenic factors and subsequently creates functional neovessels with the same pattern as that engraved in the stamp. The stamp consists of live cells that secrete angiogenic factors, an engineered hydrogel matrix that promotes cellular expression of angiogenic factors, and a three-dimensional geometry that localizes the angiogenic factors within the pattern.",

keywords = "angiogenesis, cell-encapsulation, methacrylic alginate, patterned neovessels, stereolithography",

author = "Jeong, {Jae Hyun} and Vincent Chan and Chaenyung Cha and Pinar Zorlutuna and Casey Dyck and Hsia, {K Jimmy} and Rashid Bashir and Hyunjoon Kong",

year = "2012",

month = jan,

day = "3",

doi = "10.1002/adma.201103207",

language = "English (US)",

volume = "24",

pages = "58--63",

journal = "Advanced Materials",

issn = "0935-9648",

publisher = "Wiley-VCH",

number = "1",

}

TY - JOUR

T1 - "Living" microvascular stamp for patterning of functional neovessels; Orchestrated control of matrix property and geometry

AU - Jeong, Jae Hyun

AU - Chan, Vincent

AU - Cha, Chaenyung

AU - Zorlutuna, Pinar

AU - Dyck, Casey

AU - Hsia, K Jimmy

AU - Bashir, Rashid

AU - Kong, Hyunjoon

PY - 2012/1/3

Y1 - 2012/1/3

N2 - This study presents a "living" microvascular stamp that releases multiple angiogenic factors and subsequently creates functional neovessels with the same pattern as that engraved in the stamp. The stamp consists of live cells that secrete angiogenic factors, an engineered hydrogel matrix that promotes cellular expression of angiogenic factors, and a three-dimensional geometry that localizes the angiogenic factors within the pattern.

AB - This study presents a "living" microvascular stamp that releases multiple angiogenic factors and subsequently creates functional neovessels with the same pattern as that engraved in the stamp. The stamp consists of live cells that secrete angiogenic factors, an engineered hydrogel matrix that promotes cellular expression of angiogenic factors, and a three-dimensional geometry that localizes the angiogenic factors within the pattern.

KW - angiogenesis

KW - cell-encapsulation

KW - methacrylic alginate

KW - patterned neovessels

KW - stereolithography

UR - http://www.scopus.com/inward/record.url?scp=84855279844&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84855279844&partnerID=8YFLogxK

U2 - 10.1002/adma.201103207

DO - 10.1002/adma.201103207

M3 - Article

C2 - 22109941

AN - SCOPUS:84855279844

SN - 0935-9648

VL - 24

SP - 58

EP - 63

JO - Advanced Materials

JF - Advanced Materials

IS - 1

ER -

"Living" microvascular stamp for patterning of functional neovessels; Orchestrated control of matrix property and geometry

Abstract

Keywords

ASJC Scopus subject areas

Online availability

Library availability

Related links

Fingerprint

Cite this