The influence of spatial diversity in acoustic scattering properties on estimates of the effective scatterer diameter (ESD) applied to soft biological tissues is investigated. This study is based on two-dimensional simulations of scattering media, beginning with random distributions of simple disk structures where all scattering features are known exactly. It concludes with an analysis of histology maps from healthy and fatty rabbit liver. Further, the liver histology is decomposed using an orthonormal basis to separate acoustic scattering at various spatial scales and observe how it influences ESD estimates. Overall, the goal is to quantitatively interpret ESD results for diagnostic assessments despite wide variations in tissue scatterer properties.

Original languageEnglish (US)
Pages (from-to)3677-3690
Number of pages14
JournalJournal of the Acoustical Society of America
Issue number6
StatePublished - Dec 1 2017

ASJC Scopus subject areas

  • Arts and Humanities (miscellaneous)
  • Acoustics and Ultrasonics


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