Light-triggered release of drug conjugates for an efficient combination of chemotherapy and photodynamic therapy

Lin Liu, Ruibo Wang, Chunran Wang, Jinze Wang, Li Chen, Jianjun Cheng

Research output: Contribution to journalArticle

Abstract

Herein, we present a series of light-triggered porphyrin-based polymeric drug conjugates PSDTD-m for combined chemo-photodynamic therapy of cancer. The controlled release of a drug through a ROS-cleavable linker combined with photodynamic therapy showed enhanced anticancer efficacy, proving the effectiveness of this light triggered smart nanocarrier platform for enhancing the therapy efficacy.

Original languageEnglish (US)
Pages (from-to)997-1001
Number of pages5
JournalBiomaterials Science
Volume6
Issue number5
DOIs
StatePublished - May 2018

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Photodynamic therapy
Chemotherapy
Porphyrins
Pharmaceutical Preparations

ASJC Scopus subject areas

  • Biomedical Engineering
  • Materials Science(all)

Cite this

Light-triggered release of drug conjugates for an efficient combination of chemotherapy and photodynamic therapy. / Liu, Lin; Wang, Ruibo; Wang, Chunran; Wang, Jinze; Chen, Li; Cheng, Jianjun.

In: Biomaterials Science, Vol. 6, No. 5, 05.2018, p. 997-1001.

Research output: Contribution to journalArticle

Liu, Lin ; Wang, Ruibo ; Wang, Chunran ; Wang, Jinze ; Chen, Li ; Cheng, Jianjun. / Light-triggered release of drug conjugates for an efficient combination of chemotherapy and photodynamic therapy. In: Biomaterials Science. 2018 ; Vol. 6, No. 5. pp. 997-1001.
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