Light-triggered release of drug conjugates for an efficient combination of chemotherapy and photodynamic therapy

Lin Liu, Ruibo Wang, Chunran Wang, Jinze Wang, Li Chen, Jianjun Cheng

Research output: Contribution to journalArticle

Abstract

Herein, we present a series of light-triggered porphyrin-based polymeric drug conjugates PSDTD-m for combined chemo-photodynamic therapy of cancer. The controlled release of a drug through a ROS-cleavable linker combined with photodynamic therapy showed enhanced anticancer efficacy, proving the effectiveness of this light triggered smart nanocarrier platform for enhancing the therapy efficacy.

Original languageEnglish (US)
Pages (from-to)997-1001
Number of pages5
JournalBiomaterials Science
Volume6
Issue number5
DOIs
StatePublished - May 2018

ASJC Scopus subject areas

  • Biomedical Engineering
  • Materials Science(all)

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