Light-triggered release of drug conjugates for an efficient combination of chemotherapy and photodynamic therapy

Lin Liu; Ruibo Wang; Chunran Wang; Jinze Wang; Li Chen; Jianjun Cheng

doi:10.1039/c7bm01114h

Light-triggered release of drug conjugates for an efficient combination of chemotherapy and photodynamic therapy

Lin Liu, Ruibo Wang, Chunran Wang, Jinze Wang, Li Chen, Jianjun Cheng

Research output: Contribution to journal › Article › peer-review

Abstract

Herein, we present a series of light-triggered porphyrin-based polymeric drug conjugates PSDTD-m for combined chemo-photodynamic therapy of cancer. The controlled release of a drug through a ROS-cleavable linker combined with photodynamic therapy showed enhanced anticancer efficacy, proving the effectiveness of this light triggered smart nanocarrier platform for enhancing the therapy efficacy.

Original language	English (US)
Pages (from-to)	997-1001
Number of pages	5
Journal	Biomaterials Science
Volume	6
Issue number	5
DOIs	https://doi.org/10.1039/c7bm01114h
State	Published - May 2018

ASJC Scopus subject areas

Biomedical Engineering
General Materials Science

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10.1039/c7bm01114h

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title = "Light-triggered release of drug conjugates for an efficient combination of chemotherapy and photodynamic therapy",

abstract = "Herein, we present a series of light-triggered porphyrin-based polymeric drug conjugates PSDTD-m for combined chemo-photodynamic therapy of cancer. The controlled release of a drug through a ROS-cleavable linker combined with photodynamic therapy showed enhanced anticancer efficacy, proving the effectiveness of this light triggered smart nanocarrier platform for enhancing the therapy efficacy.",

author = "Lin Liu and Ruibo Wang and Chunran Wang and Jinze Wang and Li Chen and Jianjun Cheng",

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year = "2018",

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AU - Liu, Lin

AU - Wang, Ruibo

AU - Wang, Chunran

AU - Wang, Jinze

AU - Chen, Li

AU - Cheng, Jianjun

PY - 2018/5

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Light-triggered release of drug conjugates for an efficient combination of chemotherapy and photodynamic therapy

Abstract

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