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Lewis Base Catalyzed, Sulfenium Ion Initiated Enantioselective, Spiroketalization Cascade
Kimberly M. Hilby,
Scott E. Denmark
Chemistry
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Keyphrases
Base Hydrolysis
100%
Enantioselectivity
100%
Lewis Bases
100%
Sulfenium Ion
100%
Spiroketals
100%
Spiroketalization
100%
Thiiranium Ions
75%
Good Yield
50%
Alkenes
50%
Alcohol
25%
Electron-rich
25%
Electrophilic
25%
Alkyl
25%
Nucleophile
25%
Cyclization
25%
Sulfur Source
25%
Ketones
25%
Rapid Formation
25%
Cascade-type
25%
Cascade Reaction
25%
Diastereoselectivity
25%
Enantioenriched
25%
Chiral Base
25%
Lewis Base Catalyst
25%
Substituted Styrenes
25%
Substituted Alkene
25%
Terminal Alkenes
25%
Biorelevant
25%
Chemistry
Lewis Base
100%
Spiroketal
100%
Alkene
75%
Enantioselectivity
50%
Nucleophile
25%
Styrene
25%
Ketone
25%
Cascade Reaction
25%
Diastereoselectivity
25%
Base Catalyst
25%