Larva-mediated chalkbrood resistance-associated single nucleotide polymorphism markers in the honey bee Apis mellifera

Y. Liu; L. Yan; Z. Li; W.-F. Huang; S. Pokhrei; X. Liu; S. Su

doi:10.1111/imb.12216

Larva-mediated chalkbrood resistance-associated single nucleotide polymorphism markers in the honey bee Apis mellifera

Y. Liu, L. Yan, Z. Li, W.-F. Huang, S. Pokhrei, X. Liu, S. Su

Research output: Contribution to journal › Article

Abstract

Chalkbrood is a disease affecting honey bees that seriously impairs brood growth and productivity of diseased colonies. Although honey bees can develop chalkbrood resistance naturally, the details underlying the mechanisms of resistance are not fully understood, and no easy method is currently available for selecting and breeding resistant bees. Finding the genes involved in the development of resistance and identifying single nucleotide polymorphisms (SNPs) that can be used as molecular markers of resistance is therefore a high priority. We conducted genome resequencing to compare resistant (Res) and susceptible (Sus) larvae that were selected following in vitro chalkbrood inoculation. Twelve genomic libraries, including 14.4 Gb of sequence data, were analysed using SNP-finding algorithms. Unique SNPs derived from chromosomes 2 and

Original language	English (US)
Pages (from-to)	239--250
Journal	Insect Molecular Biology
Volume	25
Issue number	3
DOIs	https://doi.org/10.1111/imb.12216
State	Published - 2016

Keywords

INHS

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10.1111/imb.12216

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Liu, Y., Yan, L., Li, Z., Huang, W-F., Pokhrei, S., Liu, X., & Su, S. (2016). Larva-mediated chalkbrood resistance-associated single nucleotide polymorphism markers in the honey bee Apis mellifera. Insect Molecular Biology, 25(3), 239--250. https://doi.org/10.1111/imb.12216

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