Larva-mediated chalkbrood resistance-associated single nucleotide polymorphism markers in the honey bee Apis mellifera

Y. Liu, L. Yan, Z. Li, W.-F. Huang, S. Pokhrei, X. Liu, S. Su

Research output: Contribution to journalArticle

Abstract

Chalkbrood is a disease affecting honey bees that seriously impairs brood growth and productivity of diseased colonies. Although honey bees can develop chalkbrood resistance naturally, the details underlying the mechanisms of resistance are not fully understood, and no easy method is currently available for selecting and breeding resistant bees. Finding the genes involved in the development of resistance and identifying single nucleotide polymorphisms (SNPs) that can be used as molecular markers of resistance is therefore a high priority. We conducted genome resequencing to compare resistant (Res) and susceptible (Sus) larvae that were selected following in vitro chalkbrood inoculation. Twelve genomic libraries, including 14.4 Gb of sequence data, were analysed using SNP-finding algorithms. Unique SNPs derived from chromosomes 2 and
Original languageEnglish (US)
Pages (from-to)239--250
JournalInsect Molecular Biology
Volume25
Issue number3
DOIs
StatePublished - 2016

Keywords

  • INHS

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