TY - JOUR
T1 - Lactate dehydrogenase and glycerol‐3‐phosphate dehydrogenase gene expression during ontogeny of the mosquito (Anopheles albimanus)
AU - Ved Brat, Sharanjit S.
AU - Whitt, Gregory S.
PY - 1974/1
Y1 - 1974/1
N2 - The specific activities (and activity per organism) of L‐lactate dehydrogenase (LDH) and glycerol‐3‐phosphate dehydrogenase (G3PDH) were determined for developmental stages of the mosquito Anopheles albimanus. The G3PDH specific activity is initially quite low, then undergoes a 5‐fold increase in the fourth instar larva. During the transitional pupal stage to adult, enzyme activity increases 25‐fold. The LDH specific activity in larval stages is initially about 100 times greater than that of G3PDH and reaches a peak in the late fourth instar larva. A 7‐fold decrease in LDH activity occurs just before moulting to early pupa. However, in contrast to reports for Drosophila, there is then a 3‐fold resurgence of LDH activity from pupal stage to the adult, mainly in the abdominal region. This is the same period in which G3PDH activity increases dramatically, primarily in the thorax. Thus, there is more than one pattern of gene expression for LDH and G3PDH within developing diptera.
AB - The specific activities (and activity per organism) of L‐lactate dehydrogenase (LDH) and glycerol‐3‐phosphate dehydrogenase (G3PDH) were determined for developmental stages of the mosquito Anopheles albimanus. The G3PDH specific activity is initially quite low, then undergoes a 5‐fold increase in the fourth instar larva. During the transitional pupal stage to adult, enzyme activity increases 25‐fold. The LDH specific activity in larval stages is initially about 100 times greater than that of G3PDH and reaches a peak in the late fourth instar larva. A 7‐fold decrease in LDH activity occurs just before moulting to early pupa. However, in contrast to reports for Drosophila, there is then a 3‐fold resurgence of LDH activity from pupal stage to the adult, mainly in the abdominal region. This is the same period in which G3PDH activity increases dramatically, primarily in the thorax. Thus, there is more than one pattern of gene expression for LDH and G3PDH within developing diptera.
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U2 - 10.1002/jez.1401870115
DO - 10.1002/jez.1401870115
M3 - Article
C2 - 4810005
AN - SCOPUS:0015973691
VL - 187
SP - 135
EP - 140
JO - Journal of Experimental Zoology
JF - Journal of Experimental Zoology
SN - 0022-104X
IS - 1
ER -