TY - JOUR
T1 - Label-free optical imaging technologies for rapid translation and use during intraoperative surgical and tumor margin assessment
AU - Boppart, Stephen A.
AU - Brown, J. Quincy
AU - Farah, Camile S.
AU - Kho, Esther
AU - Marcu, Laura
AU - Saunders, Christobel M.
AU - Sterenborg, Henricus J.C.M.
N1 - Funding Information:
We would like to thank all of our colleagues, physicians, researchers, students, staff, and patients who tirelessly engage in research to develop optical imaging technologies to improve human health. We also thank the organizers and sponsors of the 2017 International Conference on Biophotonics for their support of this effort and for offering to highlight these technologies to the international community. Finally, we thank SPIE for supporting the publication of this position paper in the Journal of Biomedical Optics. Funding to support the writing of this paper was provided in part by the National Institutes of Health (R01 CA213149 and R01 EB023232, S.A.B., and R01 CA187427 and R21 CA178578, L.M.). Research presented in this paper was partly funded by the Queensland Government Smart Futures Co-Investment Fund, Royal Brisbane and Women’s Hospital Foundation, and Cancer Australia awarded to C.S.F.
Funding Information:
Stephen A. Boppart is a cofounder and chief medical officer of Diagnostic Photonics, Inc., which is developing intraoperative optical imaging systems based on interferometric synthetic aperture microscopy. He also receives royalties from the Massachusetts Institute of Technology from licensed patents related to OCT. J. Quincy Brown is a cofounder and chief research officer for Instapath, Inc. and has a financial interest in Zenalux Biomedical, Inc. Camile S. Farah is a recipient of educational and research grants from Olympus, Inc., for oncological research on NBI. Christobel M. Saunders is a minor shareholder in OncoRes, Inc., which is developing optical coherence elastography solutions for tissue diagnostics. All other authors have nothing to disclose.
Publisher Copyright:
© 2017 Society of Photo-Optical Instrumentation Engineers.
PY - 2018/2
Y1 - 2018/2
N2 - The biannual International Conference on Biophotonics was recently held on April 30 to May 1, 2017, in Fremantle, Western Australia. This continuing conference series brought together key opinion leaders in biophotonics to present their latest results and, importantly, to participate in discussions on the future of the field and what opportunities exist when we collectively work together for using biophotonics for biological discovery and medical applications. One session in this conference, entitled "Tumor Margin Identification: Critiquing Technologies," challenged invited speakers and attendees to review and critique representative label-free optical imaging technologies and their application for intraoperative assessment and guidance in surgical oncology. We are pleased to share a summary in this outlook paper, with the intent to motivate more research inquiry and investigations, to challenge these and other optical imaging modalities to evaluate and improve performance, to spur translation and adoption, and ultimately, to improve the care and outcomes of patients.
AB - The biannual International Conference on Biophotonics was recently held on April 30 to May 1, 2017, in Fremantle, Western Australia. This continuing conference series brought together key opinion leaders in biophotonics to present their latest results and, importantly, to participate in discussions on the future of the field and what opportunities exist when we collectively work together for using biophotonics for biological discovery and medical applications. One session in this conference, entitled "Tumor Margin Identification: Critiquing Technologies," challenged invited speakers and attendees to review and critique representative label-free optical imaging technologies and their application for intraoperative assessment and guidance in surgical oncology. We are pleased to share a summary in this outlook paper, with the intent to motivate more research inquiry and investigations, to challenge these and other optical imaging modalities to evaluate and improve performance, to spur translation and adoption, and ultimately, to improve the care and outcomes of patients.
KW - Optical imaging
KW - cancer surgery
KW - label-free
KW - surgical margins
UR - http://www.scopus.com/inward/record.url?scp=85040351642&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85040351642&partnerID=8YFLogxK
U2 - 10.1117/1.JBO.23.2.021104
DO - 10.1117/1.JBO.23.2.021104
M3 - Article
C2 - 29288572
AN - SCOPUS:85040351642
SN - 1083-3668
VL - 23
JO - Journal of Biomedical Optics
JF - Journal of Biomedical Optics
IS - 2
M1 - 021104
ER -