Joint-reconstruction-enabled partial-dithering strategy for edge-illumination x-ray phase-contrast tomography

Yujia Chen, Mark A. Anastasio

Research output: Contribution to conferencePaperpeer-review


Edge illumination X-ray phase-contrast tomography (EIXPCT) is a emerging imaging technology in which partially opaque gratings are utilized with laboratory-based X-ray sources to estimate the distribution of the complex-valued refractive index. Spatial resolution in EIXPCT is mainly determined by the grating period of a sample mask, but can be significantly improved by a dithering technique in which multiple projection images are required per tomographic view angle as the object is moved over sub-pixel distances. Drawbacks of dithering include increased data acquisition times and radiation doses. Motivated by the flexibility in data acquisition designs enabled by a recently developed joint reconstruction (JR) method, a novel partial-dithering strategy for data acquisition is proposed. In this strategy, dithering is implemented at only a subset of the tomographic view angles. This results in spatial resolution that is comparable to that of the conventional full-dithering strategy where dithering is performed at every view angle, but the acquisition time is substantially decreased. The effect of dithering parameters on image resolution is explored.
Original languageEnglish (US)
StatePublished - Mar 1 2019
Externally publishedYes
EventPhysics of Medical Imaging - San Diego, United States
Duration: Feb 16 2019Feb 21 2019


ConferencePhysics of Medical Imaging


  • Joint image reconstruction
  • Phase-contrast imaging
  • Single-shot imaging

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging

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