Joint estimation of water/fat images and field inhomogeneity map

Diego Hernando, J. P. Haldar, B. P. Sutton, J. Ma, P. Kellman, Z. P. Liang

Research output: Contribution to journalArticlepeer-review


Water/fat separation in the presence of B0 field inhomogeneity is a problem of considerable practical importance in MRI. This article describes two complementary methods for estimating the water/fat images and the field inhomogeneity map from Dixon-type acquisitions. One is based on variable projection (VARPRO) and the other on linear prediction (LP). The VARPRO method is very robust and can be used in low signal-to-noise ratio conditions because of its ability to achieve the maximum-likelihood solution. The LP method is computationally more efficient, and is shown to perform well under moderate levels of noise and field Inhomogeneity. These methods have been extended to handle multicoil acquisitions by jointly solving the estimation problem for all the coils. Both methods are analyzed and compared and results from several experiments are included to demonstrate their performance.

Original languageEnglish (US)
Pages (from-to)571-580
Number of pages10
JournalMagnetic Resonance in Medicine
Issue number3
StatePublished - Mar 2008


  • Dixon imaging
  • Field map estimation
  • Linear prediction
  • Variable projection

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology


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