TY - JOUR
T1 - Isolation, characterization, and physical properties of protein antifreezes from the winter flounder, Pseudopleuronectes americanus
AU - Duman, John G.
AU - DeVries, Arthur L.
N1 - Funding Information:
This research was supported by NSF grant number OPP 74-07917, and by a NSF Graduate Student Dissertation Research Grant.
PY - 1976
Y1 - 1976
N2 - 1. 1. Three proteins with an unusual ability to depress the freezing point of water have been purified from the blood serum of the winter flounder, Pseudopleuronectes americanus. 2. 2. The amino acid compositions of these proteins are essentially the same and consist of large amounts of alanine, threonine and aspartic acid. 3. 3. The flounder protein antifreeze is quite different compositionally from the glycoprotein antifreeze previously isolated from antarctic nototheniid fishes. Therefore it seems that macromolecular antifreeze solutes have evolved independently in fishes at least twice.
AB - 1. 1. Three proteins with an unusual ability to depress the freezing point of water have been purified from the blood serum of the winter flounder, Pseudopleuronectes americanus. 2. 2. The amino acid compositions of these proteins are essentially the same and consist of large amounts of alanine, threonine and aspartic acid. 3. 3. The flounder protein antifreeze is quite different compositionally from the glycoprotein antifreeze previously isolated from antarctic nototheniid fishes. Therefore it seems that macromolecular antifreeze solutes have evolved independently in fishes at least twice.
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U2 - 10.1016/0305-0491(76)90260-1
DO - 10.1016/0305-0491(76)90260-1
M3 - Article
C2 - 1277804
AN - SCOPUS:0017118163
VL - 54
SP - 375
EP - 380
JO - Comparative Biochemistry and Physiology - B Biochemistry and Molecular Biology
JF - Comparative Biochemistry and Physiology - B Biochemistry and Molecular Biology
SN - 1096-4959
IS - 3
ER -