Is the evolution of bacterial pathogens an out-of-body experience?

Brenda A. Wilson, Abigail A. Salyers

Research output: Contribution to journalShort survey

Abstract

It has long been believed that the complex interactions between pathogens and the hosts they infect are the primary driving forces that determine the strategies used by microorganisms to counter host defenses. However, new evidence suggests that the external environment, including other hosts, might have a greater role in the evolution of certain pathogens than previously thought. In particular, acquisition of virulence traits through horizontal gene transfer might occur at high frequency through microbial contacts in the environment, either as mixed microbial soups in the guts of insects or other vectors, or as soil or aquatic biofilms. Should microbiologists be alarmed about the unknown risks posed by bacteria gaining potentially dangerous traits from external environmental, or even extraterrestrial, sources?

Original languageEnglish (US)
Pages (from-to)347-350
Number of pages4
JournalTrends in Microbiology
Volume11
Issue number8
DOIs
StatePublished - Aug 2003

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Host-Pathogen Interactions
Horizontal Gene Transfer
Biofilms
Virulence
Insects
Soil
Bacteria

ASJC Scopus subject areas

  • Microbiology
  • Microbiology (medical)
  • Infectious Diseases
  • Virology

Cite this

Is the evolution of bacterial pathogens an out-of-body experience? / Wilson, Brenda A.; Salyers, Abigail A.

In: Trends in Microbiology, Vol. 11, No. 8, 08.2003, p. 347-350.

Research output: Contribution to journalShort survey

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