Abstract
In aqueous medium, base-induced aldol condensations of keto aldehyde 1 show high anti-selectivity independent of metal ion and water content of the solvent. The acid-induced aldol condensations affords syn-aldol products in variable selectivity depending upon acid strength and water content of the medium.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 7729-7732 |
| Number of pages | 4 |
| Journal | Tetrahedron Letters |
| Volume | 33 |
| Issue number | 50 |
| DOIs | |
| State | Published - Dec 8 1993 |
Keywords
- Aldol Condensation
- Antiperiplanar
- Aqueous Solvent
- Syn- and Anti-aldol
- Synclinal
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry
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