TY - GEN
T1 - Investigation of limited-view image reconstruction in optoacoustic tomography employing a priori structural information
AU - Huang, Chao
AU - Oraevsky, Alexander A.
AU - Anastasio, Mark A.
PY - 2010
Y1 - 2010
N2 - Optoacoustic tomography (OAT) is an emerging ultrasound-mediated biophotonic imaging modality that has exciting potential for many biomedical imaging applications. There is great interest in conducting B-mode ultrasound and OAT imaging studies for breast cancer detection using a common transducer. In this situation, the range of tomographic view angles is limited, which can result in distortions in the reconstructed OAT image if conventional reconstruction algorithms are applied to limited-view measurement data. In this work, we investigate an image reconstruction method that utilizes information regarding target boundaries to improve the quality of the reconstructed OAT images. This is accomplished by developing boundary-constrained image reconstruction algorithm for OAT based on Bayesian image reconstruction theory. The computer-simulation studies demonstrate that the Bayesian approach can effectively reduce the artifact and noise levels and preserve the edges in reconstructed limited-view OAT images as compared to those produced by a conventional OAT reconstruction algorithm.
AB - Optoacoustic tomography (OAT) is an emerging ultrasound-mediated biophotonic imaging modality that has exciting potential for many biomedical imaging applications. There is great interest in conducting B-mode ultrasound and OAT imaging studies for breast cancer detection using a common transducer. In this situation, the range of tomographic view angles is limited, which can result in distortions in the reconstructed OAT image if conventional reconstruction algorithms are applied to limited-view measurement data. In this work, we investigate an image reconstruction method that utilizes information regarding target boundaries to improve the quality of the reconstructed OAT images. This is accomplished by developing boundary-constrained image reconstruction algorithm for OAT based on Bayesian image reconstruction theory. The computer-simulation studies demonstrate that the Bayesian approach can effectively reduce the artifact and noise levels and preserve the edges in reconstructed limited-view OAT images as compared to those produced by a conventional OAT reconstruction algorithm.
KW - Bayesian image reconstruction
KW - limited-view tomography
KW - optoacoustic tomography
KW - photoacoustic tomography
UR - http://www.scopus.com/inward/record.url?scp=78049362794&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=78049362794&partnerID=8YFLogxK
U2 - 10.1117/12.861005
DO - 10.1117/12.861005
M3 - Conference contribution
AN - SCOPUS:78049362794
SN - 9780819482969
T3 - Proceedings of SPIE - The International Society for Optical Engineering
BT - Image Reconstruction from Incomplete Data VI
T2 - Image Reconstruction from Incomplete Data VI
Y2 - 2 August 2010 through 3 August 2010
ER -