Introducing Students to Surface Modification and Phase Transfer of Nanoparticles with a Laboratory Experiment

Alaaldin M. Alkilany; Sara Mansour; Hamza M. Amro; Beatriz Pelaz; Mahmoud G. Soliman; Joshua G. Hinman; Jordan M. Dennison; Wolfgang J. Parak; Catherine J. Murphy

doi:10.1021/acs.jchemed.6b01003

Introducing Students to Surface Modification and Phase Transfer of Nanoparticles with a Laboratory Experiment

Alaaldin M. Alkilany, Sara Mansour, Hamza M. Amro, Beatriz Pelaz, Mahmoud G. Soliman, Joshua G. Hinman, Jordan M. Dennison, Wolfgang J. Parak, Catherine J. Murphy

Research output: Contribution to journal › Article › peer-review

Abstract

A simple, reliable, and cost-effective experiment is presented in which students synthesized citrate-capped gold nanoparticles (GNPs), functionalized them with poly(ethylene glycol) (PEG), and transferred the PEG-GNPs from water to the organic phase dichloromethane. The experiment introduces students to nanotechnology with foci on important concepts including surface modification of nanoparticles, colloidal stability, and phase transfer. The proposed experiment was evaluated at three different universities to confirm its reproducibility and versatility. Collectively, the proposed experiment is suitable to be implemented into colloid- or nanoscience-related curricula.

Original language	English (US)
Pages (from-to)	769-774
Number of pages	6
Journal	Journal of Chemical Education
Volume	94
Issue number	6
DOIs	https://doi.org/10.1021/acs.jchemed.6b01003
State	Published - Jun 13 2017

Keywords

Colloids
Demonstrations
Hands-On Learning/Manipulatives
Laboratory Instruction
Nanotechnology
Upper-Division Undergraduate

ASJC Scopus subject areas

Chemistry(all)
Education

Access to Document

10.1021/acs.jchemed.6b01003

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Introducing Students to Surface Modification and Phase Transfer of Nanoparticles with a Laboratory Experiment. / Alkilany, Alaaldin M.; Mansour, Sara; Amro, Hamza M.; Pelaz, Beatriz; Soliman, Mahmoud G.; Hinman, Joshua G.; Dennison, Jordan M.; Parak, Wolfgang J.; Murphy, Catherine J.

In: Journal of Chemical Education, Vol. 94, No. 6, 13.06.2017, p. 769-774.

Research output: Contribution to journal › Article › peer-review

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abstract = "A simple, reliable, and cost-effective experiment is presented in which students synthesized citrate-capped gold nanoparticles (GNPs), functionalized them with poly(ethylene glycol) (PEG), and transferred the PEG-GNPs from water to the organic phase dichloromethane. The experiment introduces students to nanotechnology with foci on important concepts including surface modification of nanoparticles, colloidal stability, and phase transfer. The proposed experiment was evaluated at three different universities to confirm its reproducibility and versatility. Collectively, the proposed experiment is suitable to be implemented into colloid- or nanoscience-related curricula.",

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