Introducing Students to Surface Modification and Phase Transfer of Nanoparticles with a Laboratory Experiment

Alaaldin M. Alkilany, Sara Mansour, Hamza M. Amro, Beatriz Pelaz, Mahmoud G. Soliman, Joshua G. Hinman, Jordan M. Dennison, Wolfgang J. Parak, Catherine J. Murphy

Research output: Contribution to journalArticle

Abstract

A simple, reliable, and cost-effective experiment is presented in which students synthesized citrate-capped gold nanoparticles (GNPs), functionalized them with poly(ethylene glycol) (PEG), and transferred the PEG-GNPs from water to the organic phase dichloromethane. The experiment introduces students to nanotechnology with foci on important concepts including surface modification of nanoparticles, colloidal stability, and phase transfer. The proposed experiment was evaluated at three different universities to confirm its reproducibility and versatility. Collectively, the proposed experiment is suitable to be implemented into colloid- or nanoscience-related curricula.

Original languageEnglish (US)
Pages (from-to)769-774
Number of pages6
JournalJournal of Chemical Education
Volume94
Issue number6
DOIs
StatePublished - Jun 13 2017

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Keywords

  • Colloids
  • Demonstrations
  • Hands-On Learning/Manipulatives
  • Laboratory Instruction
  • Nanotechnology
  • Upper-Division Undergraduate

ASJC Scopus subject areas

  • Chemistry(all)
  • Education

Cite this

Alkilany, A. M., Mansour, S., Amro, H. M., Pelaz, B., Soliman, M. G., Hinman, J. G., Dennison, J. M., Parak, W. J., & Murphy, C. J. (2017). Introducing Students to Surface Modification and Phase Transfer of Nanoparticles with a Laboratory Experiment. Journal of Chemical Education, 94(6), 769-774. https://doi.org/10.1021/acs.jchemed.6b01003