TY - JOUR
T1 - Intrauterine devices and endometrial cancer
AU - Rosenblatt, Karin A.
AU - Thomas, David B.
AU - Berry, Geoffrey
AU - MacLennan, Robert
AU - Shearman, Rodney
AU - Jelihovsky, Tatiana
AU - Booth, Joan Cooper
AU - Molina, Ramiro
AU - Martinez, Luis
AU - Salas, Oriana
AU - Dabancens, Alfredo
AU - Zhiheng, Chen
AU - Yun, Tao
AU - Wei, Hu Yong
AU - Modan, Baruch
AU - Ron, Elaine
AU - Alfandary, Esther
AU - Rodriguez Cuevas, Hector
AU - Benavides Salazar, Socorro
AU - Palet, Antonio
AU - Ontiveros, Patricia
AU - Apelo, Ruben A.
AU - De La Cruz, Julietta R.
AU - Baens, Jose
AU - Javier, Benita
AU - Silpisornkosol, Suporn
AU - Pardthaisong, Tieng
AU - Martin, Nimit
AU - Theetranont, Choti
AU - Boosiri, Banpot
AU - Chutivongse, Supawat
AU - Virutamasen, Pramuan
AU - Wongsrichanalai, Chansuda
AU - Jimakorn, Prasarn
AU - Koetsawang, Suporn
AU - Rachawat, Daungdao
AU - Chantarakul, Nivat
AU - Langley, F. A.
AU - Noonan, Elizabeth A.
AU - Hoick, Susan
AU - Farley, Tim
AU - Meirik, Olav
N1 - This research received primary financial support from the Special Programme of Research, Development and Research Training in Human Reproduction, World Health Organization; supplemental support from Contract No. NICHD-CE-84-16 from the US National Institute of Child Health and Human Development.
PY - 1996/12
Y1 - 1996/12
N2 - The relationship between intrauterine device (IUD) use and the development of endometrial cancer was assessed in data from seven countries that were collected between 1979 and 1988 for a multinational hospital-based case-control study. Two hundred twenty-six cases of endometrial cancer were compared with 1,529 controls matched for age, hospital, and year of interview. No significant association between use of an IUD and risk of endometrial cancer was observed (OR = 0.74, 95% CI = 0.4-1.33). There were no trends in risk with respect to duration of use, time since first use, or ages at first or last use. No cases had used a copper IUD (OR = 0, 95% CI = 0- 1.71). Although women over age 55 who had used an IUD were at significantly increased risk, this unexpected finding is based on small numbers of users and requires independent confirmation. These results, along with those from other studies, provide reassurance that risk of endometrial cancer is unlikely to be increased by use of an IUD.
AB - The relationship between intrauterine device (IUD) use and the development of endometrial cancer was assessed in data from seven countries that were collected between 1979 and 1988 for a multinational hospital-based case-control study. Two hundred twenty-six cases of endometrial cancer were compared with 1,529 controls matched for age, hospital, and year of interview. No significant association between use of an IUD and risk of endometrial cancer was observed (OR = 0.74, 95% CI = 0.4-1.33). There were no trends in risk with respect to duration of use, time since first use, or ages at first or last use. No cases had used a copper IUD (OR = 0, 95% CI = 0- 1.71). Although women over age 55 who had used an IUD were at significantly increased risk, this unexpected finding is based on small numbers of users and requires independent confirmation. These results, along with those from other studies, provide reassurance that risk of endometrial cancer is unlikely to be increased by use of an IUD.
KW - developing countries
KW - endometrial neoplasms
KW - intrauterine devices
UR - https://www.scopus.com/pages/publications/0030561080
UR - https://www.scopus.com/pages/publications/0030561080#tab=citedBy
U2 - 10.1016/S0010-7824(96)00199-0
DO - 10.1016/S0010-7824(96)00199-0
M3 - Article
C2 - 8968660
AN - SCOPUS:0030561080
SN - 0010-7824
VL - 54
SP - 329
EP - 332
JO - Contraception
JF - Contraception
IS - 6
ER -