Intramembranous particle distribution and filipin binding in dysplastic canine retina

H. E. Whiteley; R. A. Bergstrom; J. R. Scott

doi:10.3109/02713689109020346

Intramembranous particle distribution and filipin binding in dysplastic canine retina

H. E. Whiteley, R. A. Bergstrom, J. R. Scott

Research output: Contribution to journal › Article › peer-review

Abstract

We examined dysplastic canine retina for changes in intramembranous particle (IMP) density and filipin binding to sterols. Differences in IMP density were identified in incipiently dysplastic fetal retina and also in the degree of filipin binding near the onset of the dysplastic process. The data suggest that there are temporal differences in IMPs and filipin-sterol complexes that may be related to the formation of retinal folds and disorganized dysplastic retina proliferation.

Original language	English (US)
Pages (from-to)	1069-1074
Number of pages	6
Journal	Current Eye Research
Volume	10
Issue number	11
DOIs	https://doi.org/10.3109/02713689109020346
State	Published - 1991

ASJC Scopus subject areas

Ophthalmology
Sensory Systems
Cellular and Molecular Neuroscience

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10.3109/02713689109020346

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@article{e5583fff8da4472d82a47f3095b12de7,

title = "Intramembranous particle distribution and filipin binding in dysplastic canine retina",

abstract = "We examined dysplastic canine retina for changes in intramembranous particle (IMP) density and filipin binding to sterols. Differences in IMP density were identified in incipiently dysplastic fetal retina and also in the degree of filipin binding near the onset of the dysplastic process. The data suggest that there are temporal differences in IMPs and filipin-sterol complexes that may be related to the formation of retinal folds and disorganized dysplastic retina proliferation.",

author = "Whiteley, {H. E.} and Bergstrom, {R. A.} and Scott, {J. R.}",

note = "Funding Information: ACKNOWLEDGEMENTS The excellent technical assistance of Mses. M. Noonan and L. Pitner is gratefully acknowledged. We thank the Center for Electron Microscopy, University of Illinois, for use of the freeze-fracture equipment and the Word Processing Center for manuscript preparation. This work was supported by NIH Grant EY07202.",

year = "1991",

doi = "10.3109/02713689109020346",

language = "English (US)",

volume = "10",

pages = "1069--1074",

journal = "Current Eye Research",

issn = "0271-3683",

publisher = "Taylor and Francis Ltd.",

number = "11",

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TY - JOUR

T1 - Intramembranous particle distribution and filipin binding in dysplastic canine retina

AU - Whiteley, H. E.

AU - Bergstrom, R. A.

AU - Scott, J. R.

N1 - Funding Information: ACKNOWLEDGEMENTS The excellent technical assistance of Mses. M. Noonan and L. Pitner is gratefully acknowledged. We thank the Center for Electron Microscopy, University of Illinois, for use of the freeze-fracture equipment and the Word Processing Center for manuscript preparation. This work was supported by NIH Grant EY07202.

PY - 1991

Y1 - 1991

N2 - We examined dysplastic canine retina for changes in intramembranous particle (IMP) density and filipin binding to sterols. Differences in IMP density were identified in incipiently dysplastic fetal retina and also in the degree of filipin binding near the onset of the dysplastic process. The data suggest that there are temporal differences in IMPs and filipin-sterol complexes that may be related to the formation of retinal folds and disorganized dysplastic retina proliferation.

AB - We examined dysplastic canine retina for changes in intramembranous particle (IMP) density and filipin binding to sterols. Differences in IMP density were identified in incipiently dysplastic fetal retina and also in the degree of filipin binding near the onset of the dysplastic process. The data suggest that there are temporal differences in IMPs and filipin-sterol complexes that may be related to the formation of retinal folds and disorganized dysplastic retina proliferation.

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JF - Current Eye Research

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ER -

Intramembranous particle distribution and filipin binding in dysplastic canine retina

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