Optical coherence tomography (OCT) is an optical ranging technique analogous to radar - detection of back-scattered light produces a signal that is temporally localized at times-of-flight corresponding to the location of scatterers in the object. However the interferometric collection technique used in OCT allows, in principle, the coherent collection of data, i.e. amplitude and phase information can be extracted. Interferometric Synthetic Aperture Microscopy (ISAM) adds phase-stable data collection to OCT instrumentation and employs physics-based processing analogous to that used in Synthetic Aperture Radar (SAR). That is, the complex nature of the coherent data is exploited to give gains in image quality. Specifically, diffraction-limited resolution is achieved throughout the sample, not just within focal volume of the illuminating field. Simulated and experimental verifications of this effect are presented. ISAM's computational focusing obviates the trade-off between lateral resolution and depth-of-focus seen in traditional OCT.

Original languageEnglish (US)
Title of host publication2007 IEEE International Conference on Image Processing, ICIP 2007 Proceedings
PublisherIEEE Computer Society
Number of pages4
ISBN (Print)1424414377, 9781424414376
StatePublished - 2007
Event14th IEEE International Conference on Image Processing, ICIP 2007 - San Antonio, TX, United States
Duration: Sep 16 2007Sep 19 2007

Publication series

NameProceedings - International Conference on Image Processing, ICIP
ISSN (Print)1522-4880


Other14th IEEE International Conference on Image Processing, ICIP 2007
Country/TerritoryUnited States
CitySan Antonio, TX


  • Image reconstruction
  • Inverse problems
  • Microscopy
  • Optical interferometry
  • Optical tomography

ASJC Scopus subject areas

  • Engineering(all)


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