Integration of statistical models and visualization tools to characterize microRNA networks influencing cancer

James Karnia; Kristin R. Delfino; Maria Bonita Villamil; Gustavo Caetano-Anolles; Sandra Luisa Rodriguez-Zas

doi:10.1109/BIBMW.2011.6112541

Integration of statistical models and visualization tools to characterize microRNA networks influencing cancer

James Karnia, Kristin R. Delfino, Maria Bonita Villamil, Gustavo Caetano-Anolles, Sandra Luisa Rodriguez-Zas

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Gene expression microarray experiments can be used to infer the topology of co-expression networks between genes in the immune-system pathways. Immune-system pathways are highly dimensional, including numerous gene nodes and edges connecting nodes. A bioinformatics strategy to infer and confirm gene co-expression networks was developed and applied to two major immune-system pathways. In total, 182 and 356 co-expression profiles between pairs of genes were identified in the NOD-like and B-cell receptor signaling pathways. The distinct distribution of the sign of the relationships among the pathways offered additional insights into the network.

Original language	English (US)
Title of host publication	2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2011
Pages	1009-1011
Number of pages	3
DOIs	https://doi.org/10.1109/BIBMW.2011.6112541
State	Published - Dec 1 2011
Event	2011 IEEE International Conference onBioinformatics and Biomedicine Workshops, BIBMW 2011 - Atlanta, GA, United States Duration: Nov 12 2011 → Nov 15 2011

Publication series

Name	2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2011

Other

Other	2011 IEEE International Conference onBioinformatics and Biomedicine Workshops, BIBMW 2011
Country	United States
City	Atlanta, GA
Period	11/12/11 → 11/15/11

Keywords

B-cell receptor
Cytokine
NOD-like receptor
chemokine
microarray

ASJC Scopus subject areas

Biomedical Engineering
Health Informatics
Health Information Management

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Cite this

Karnia, J., Delfino, K. R., Villamil, M. B., Caetano-Anolles, G., & Rodriguez-Zas, S. L. (2011). Integration of statistical models and visualization tools to characterize microRNA networks influencing cancer. In 2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2011 (pp. 1009-1011). [6112541] (2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2011). https://doi.org/10.1109/BIBMW.2011.6112541

Integration of statistical models and visualization tools to characterize microRNA networks influencing cancer. / Karnia, James; Delfino, Kristin R.; Villamil, Maria Bonita ; Caetano-Anolles, Gustavo ; Rodriguez-Zas, Sandra Luisa.

2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2011. 2011. p. 1009-1011 6112541 (2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2011).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Karnia, J, Delfino, KR, Villamil, MB , Caetano-Anolles, G & Rodriguez-Zas, SL 2011, Integration of statistical models and visualization tools to characterize microRNA networks influencing cancer. in 2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2011., 6112541, 2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2011, pp. 1009-1011, 2011 IEEE International Conference onBioinformatics and Biomedicine Workshops, BIBMW 2011, Atlanta, GA, United States, 11/12/11. https://doi.org/10.1109/BIBMW.2011.6112541

Karnia J, Delfino KR, Villamil MB , Caetano-Anolles G , Rodriguez-Zas SL. Integration of statistical models and visualization tools to characterize microRNA networks influencing cancer. In 2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2011. 2011. p. 1009-1011. 6112541. (2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2011). https://doi.org/10.1109/BIBMW.2011.6112541

Karnia, James ; Delfino, Kristin R. ; Villamil, Maria Bonita ; Caetano-Anolles, Gustavo ; Rodriguez-Zas, Sandra Luisa. / Integration of statistical models and visualization tools to characterize microRNA networks influencing cancer. 2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2011. 2011. pp. 1009-1011 (2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2011).

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