Nanowire field effect transistors (FETs) have been widely used as sensors for detection of biological products including small molecules, proteins, and nucleic acids [1]. Biological FET's provide high sensitivity, small size, portability and low cost making them an attractive option for 'lab-on-a-chip' applications [2]. Our research aims to take 'lab-on-a-chip' technology one step further by introducing the concept of a 'lab-on-a-transistor'. In this methodology, laboratory operations are performed individually on a single transistor instead of on an entire microchip. To demonstrate this concept, our group has developed a heating technique that allows transistors to act as electrically addressable, individual heating units. We have coupled the transistor heaters with placement of sub-nanoliter droplets to create individual heated reaction volumes (see Figure 1). Under this configuration FET devices become highly localized heater/sensor-hybrids capable of high-speed thermocycling of <1nL reactions with potential for electrical detection of biological analytes.

Original languageEnglish (US)
Title of host publication2012 IEEE Photonics Conference, IPC 2012
Number of pages2
StatePublished - 2012
Event25th IEEE Photonics Conference, IPC 2012 - Burlingame, CA, United States
Duration: Sep 23 2012Sep 27 2012

Publication series

Name2012 IEEE Photonics Conference, IPC 2012


Other25th IEEE Photonics Conference, IPC 2012
Country/TerritoryUnited States
CityBurlingame, CA

ASJC Scopus subject areas

  • Electrical and Electronic Engineering


Dive into the research topics of 'Integrated lab on chip for detection of cells and micro-organisms'. Together they form a unique fingerprint.

Cite this