@inproceedings{7f6eefbf9e08498b89aa78adaa6af5b8,
title = "Integrated 'lab-on-a-transistor': With droplets-in-air for parallel nanoliter reactions",
abstract = "We aim to take 'lab-on-chip' technology further by introducing the concept of a 'lab-on-transistor'. In this methodology, laboratory operations, such as heating, cell lysis, and detection, are performed on a single transistor instead of on an entire microchip. To demonstrate this concept, we developed a heating technique that allows transistors to act as electrically addressable, individual heating units. We have coupled the transistor heaters with placement of sub-nanoliter droplets to create individual heated reaction volumes. Under this configuration transistors become highly localized heater/sensors capable of high-speed thermocycling (>25°C/s) of <1nL reactions with potential for electrical detection of biological analytes.",
keywords = "Denaturation, Droplets, Electroporation, Field effect transistor, Parallel, PCR",
author = "Eric Salm and Carlos Duarte and Nima Jokilaakso and Rashid Bashir",
year = "2012",
language = "English (US)",
isbn = "9780979806452",
series = "Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012",
publisher = "Chemical and Biological Microsystems Society",
pages = "1945--1947",
booktitle = "Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012",
note = "16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012 ; Conference date: 28-10-2012 Through 01-11-2012",
}