Innovations in CRISPR technology

Alexandra K. Brooks, Thomas Gaj

Research output: Contribution to journalReview article

Abstract

CRISPR-Cas9 is a versatile tool for genome engineering that has revolutionized biotechnology and is poised to impact medicine. Recent advances in the identification of unique CRISPR systems, as well as the re-engineering of the Cas9 protein for expanded function, has enabled the diversification of the CRISPR genome engineering toolbox. In this review, we highlight these innovations and discuss how advances in CRISPR technology can lead to breakthroughs in the field of gene therapy.

Original languageEnglish (US)
Pages (from-to)95-101
Number of pages7
JournalCurrent Opinion in Biotechnology
Volume52
DOIs
StatePublished - Aug 2018

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering
  • Biomedical Engineering

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