Injectable, cellular-scale optoelectronics with applications for wireless optogenetics

Tae Il Kim, Jordan G. McCall, Yei Hwan Jung, Xian Huang, Edward R. Siuda, Yuhang Li, Jizhou Song, Young Min Song, Hsuan An Pao, Rak Hwan Kim, Chaofeng Lu, Sung Dan Lee, Il Sun Song, Gunchul Shin, Ream Al-Hasani, Stanley Kim, Meng Peun Tan, Yonggang Huang, Fiorenzo G. Omenetto, John A. RogersMichael R. Bruchas

Research output: Contribution to journalArticlepeer-review


Successful integration of advanced semiconductor devices with biological systems will accelerate basic scientific discoveries and their translation into clinical technologies. In neuroscience generally, and in optogenetics in particular, the ability to insert light sources, detectors, sensors, and other components into precise locations of the deep brain yields versatile and important capabilities. Here, we introduce an injectable class of cellular-scale optoelectronics that offers such features, with examples of unmatched operational modes in optogenetics, including completely wireless and programmed complex behavioral control over freely moving animals. The ability of these ultrathin, mechanically compliant, biocompatible devices to afford minimally invasive operation in the soft tissues of the mammalian brain foreshadow applications in other organ systems, with potential for broad utility in biomedical science and engineering.

Original languageEnglish (US)
Pages (from-to)211-216
Number of pages6
Issue number6129
StatePublished - Apr 12 2013

ASJC Scopus subject areas

  • General


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