Abstract
The metabolic inhibitors acetaminophen, 7,8-benzoflavone, and methimazle significantly reduced the mutagenicity of the promutagen N-nitrosodimethylamine in the higher plant Arabidopsis thaliana. In contrast, these metabolic inhibitors had no effect on the mutagenicity of the direct-acting mutagen N-methyl-N′-nitro-N-nitrosoguanidine.
Original language | English (US) |
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Pages (from-to) | 57-61 |
Number of pages | 5 |
Journal | Mutation Research/Genetic Toxicology |
Volume | 300 |
Issue number | 1 |
DOIs | |
State | Published - Jun 1993 |
Externally published | Yes |
Keywords
- 7,8-Benzoflavone
- Acetaminophen
- Arabidopsis thaliana
- Methimazole
- Mutagenicity inhibition
ASJC Scopus subject areas
- Toxicology
- Genetics