Keyphrases
Hexokinase
100%
Bisphosphonates
100%
Trypanosoma Cruzi (T. cruzi)
100%
IC50
25%
IC50 Value
25%
Comparative Molecular Similarity Indices Analysis (CoMSIA)
25%
Hydrolysable
12%
Electrostatic Interaction
12%
Hydrophobic Interaction
12%
Clinically Significant
12%
Glycolysis
12%
Human Cell Lines
12%
Active Compounds
12%
Steric Interactions
12%
Enzyme Inhibition
12%
Diphosphate
12%
Potent Inhibitor
12%
Selective Activity
12%
Etiological Agents
12%
Dictyostelium Discoideum
12%
Chagas Disease
12%
Trypanosoma Brucei
12%
Human Enzymes
12%
Pharmacophore
12%
Intracellular Amastigotes
12%
Amastigote
12%
African Sleeping Sickness
12%
Medicine and Dentistry
Bisphosphonate
100%
Trypanosoma Cruzi
100%
Hexokinase
100%
IC50
80%
Cell Line
20%
Pyrophosphate
20%
Chagas Disease
20%
Pharmacophore
20%
African Trypanosomiasis
20%
Trypanosoma Brucei
20%
Enzyme Inhibition
20%
Pharmacology, Toxicology and Pharmaceutical Science
Bisphosphonic Acid Derivative
100%
Trypanosoma Cruzi
100%
Hexokinase
100%
IC50
80%
Chagas Disease
20%
Dictyostelium discoideum
20%
Pyrophosphate
20%
Enzyme Inhibition
20%
Amastigote
20%
Trypanosoma Brucei
20%
African Trypanosomiasis
20%
Biochemistry, Genetics and Molecular Biology
Trypanosoma Cruzi
100%
Hexokinase
100%
IC50
80%
Enzyme
60%
Comparative Molecular Similarity Indices Analysis
40%
Pyrophosphate
20%
Dictyostelium discoideum
20%
Enzyme Inhibition
20%
Pharmacophore
20%
Amastigote
20%
Trypanosoma Brucei
20%
Immunology and Microbiology
IC50
100%
Trypanosoma Cruzi
100%
Comparative Molecular Similarity Indices Analysis
50%
Cell Line
25%
Human Cell
25%
Dictyostelium discoideum
25%
Enzyme Inhibition
25%
Trypanosoma Brucei
25%
Pharmacophore
25%
Chagas Disease
25%
Amastigote
25%