Influence of attractants and repellents on methyl group turnover on methyl-accepting chemotaxis proteins of Bacillus subtilis and role of CheW

D. W. Hanlon, P. B. Carpenter, G. W. Ordal

Research output: Contribution to journalArticle

Abstract

The ability of attractants and repellents to affect the turnover of methyl groups on the methyl-accepting chemotaxis proteins (MCPs) was examined for Bacillus subtilis. Attractants were found to cause an increase in the turnover of methyl groups esterified to the MCPs, while repellents caused a decrease. These reactions do not require CheW. However, a cheW null mutant exhibits enhanced turnover in unstimulated cells. Assuming that the turnover of methyl groups on the MCPs reflects a change in the activity of CheA, these results suggest that the activation of CheA via chemoeffector binding at the receptor does not require CheW.

Original languageEnglish (US)
Pages (from-to)4218-4222
Number of pages5
JournalJournal of bacteriology
Volume174
Issue number13
DOIs
StatePublished - Jan 1 1992

ASJC Scopus subject areas

  • Microbiology
  • Molecular Biology

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