Industrial biotechnology: Tools and applications

Weng Lin Tang, Huimin Zhao

Research output: Contribution to journalReview articlepeer-review


Industrial biotechnology involves the use of enzymes and microorganisms to produce value-added chemicals from renewable sources. Because of its association with reduced energy consumption, greenhouse gas emissions, and waste generation, industrial biotechnology is a rapidly growing field. Here we highlight a variety of important tools for industrial biotechnology, including protein engineering, metabolic engineering, synthetic biology, systems biology, and downstream processing. In addition, we show how these tools have been successfully applied in several case studies, including the production of 1,3-propanediol, lactic acid, and biofuels. It is expected that industrial biotechnology will be increasingly adopted by chemical, pharmaceutical, food, and agricultural industries.

Original languageEnglish (US)
Pages (from-to)1725-1739
Number of pages15
JournalBiotechnology Journal
Issue number12
StatePublished - Dec 2009


  • Biocatalysis
  • Bioenergy
  • Metabolic engineering
  • Protein engineering

ASJC Scopus subject areas

  • Applied Microbiology and Biotechnology
  • Molecular Medicine


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