Induction of p21 and p27 expression by amino acid deprivation of HepG2 human hepatoma cells involves mRNA stabilization

Keyphrases

• Histidine 100%
• HepG2 Cancer Cells 100%
• Amino Acid Starvation 100%
• P21 Expression 100%
• P27 Expression 100%
• Amino Acids 66%
• Amino Acid Limitation 66%
• Phosphorylation 33%
• Signal Transduction Pathway 33%
• P53 Protein 33%
• Screening Study 33%
• Phosphoinositide 3-kinase (PI3K) 33%
• Gene number 33%
• ERK2 33%
• Cell Cycle Regulators 33%
• MRNA Abundance 33%
• Cell Cycle Control 33%
• G1 Phase 33%
• HepG2 Cells 33%
• Mammalian Target of Rapamycin Pathway 33%
• Starvation 33%
• De Novo Protein Synthesis 33%
• Post-transcriptional 33%
• Extracellular Signal-regulated Kinase 33%
• Deprivation 33%
• Amino Acid Availability 33%
• ERK Pathway 33%
• ERK1 33%
• Cyclin-dependent Kinase Inhibitor p27 33%
• Cyclin-dependent Kinase Inhibitor p21 33%
• P53 Transactivation 33%

Biochemistry, Genetics and Molecular Biology

• Amino Acids 100%
• P21 100%
• Messenger RNA 100%
• Histidine 37%
• P53 25%
• Signal Transduction 12%
• Transactivation 12%
• Protein Biosynthesis 12%
• Cell Cycle 12%
• Mechanistic Target of Rapamycin 12%
• Phosphoinositide 3-Kinase 12%
• Cyclin-Dependent Kinase 12%
• Essential Amino Acid 12%
• Extracellular Signal-Regulated Kinases 12%
• G1 Phase 12%
• Cell Cycle Regulation 12%

Pharmacology, Toxicology and Pharmaceutical Science

• Amino Acid 100%
• Liver Cell Carcinoma 100%
• Messenger RNA 100%
• Histidine 37%
• Protein P53 25%
• Mammalian Target of Rapamycin 12%
• Mitogen Activated Protein Kinase 12%
• Mitogen Activated Protein Kinase 3 12%
• Phosphatidylinositol 3 Kinase 12%
• Essential Amino Acid 12%
• Cyclin Dependent Kinase Inhibitor 1A 12%
• Cyclin Dependent Kinase Inhibitor 1B 12%
• Mitogen Activated Protein Kinase 1 12%