TY - JOUR
T1 - Increasing the separation of block cryoconcentration through a novel centrifugal filter-based method
AU - Orellana-Palma, Patricio
AU - Takhar, Pawan S.
AU - Petzold, Guillermo
N1 - Funding Information:
Guillermo Petzold); and USDA-NIFA under Grant No. 2015-67017-23074 (Dr. Pawan Takhar);Comisión Nacional de Investigación Científica y Tecnológica [FONDECYT Project No. 11140747 (Dr. Guillermo Petzo,Human Capital Formation Advanced Program National].
Funding Information:
This work was supported by CONICYT–Chile under the Grant Human Capital Formation Advanced Program National Doctoral Fellowship 2016 (Folio No. 21160514, P. Orellana-Palma); the FONDECYT Project No. 11140747 (Dr.
Publisher Copyright:
© 2018, © 2018 Taylor & Francis.
PY - 2019/3/24
Y1 - 2019/3/24
N2 - The objective of this work was to evaluate the filter addition in centrifugal cryoconcentration. The cryoconcentration process was optimized by Response Surface Method using initial concentration (C 0 ) and centrifugation speed (CS) (independent variables) and efficiency (η), percentage of concentrate (PC) and solute yield (Y) (dependent variables), under radial and axial freezing conditions. The optimal interactions were 5 (wt.%), 3850 rpm and axial condition, with high final solute concentration, and extraordinary separation, with 86%, 63% and 0.87 (kg/kg) for η, PC and Y, respectively. Therefore, the centrifugal filter cryoconcentration allowed the migration of solutes between the crystals, and the filter improved the separation and elution process of the concentrated solution from the ice.
AB - The objective of this work was to evaluate the filter addition in centrifugal cryoconcentration. The cryoconcentration process was optimized by Response Surface Method using initial concentration (C 0 ) and centrifugation speed (CS) (independent variables) and efficiency (η), percentage of concentrate (PC) and solute yield (Y) (dependent variables), under radial and axial freezing conditions. The optimal interactions were 5 (wt.%), 3850 rpm and axial condition, with high final solute concentration, and extraordinary separation, with 86%, 63% and 0.87 (kg/kg) for η, PC and Y, respectively. Therefore, the centrifugal filter cryoconcentration allowed the migration of solutes between the crystals, and the filter improved the separation and elution process of the concentrated solution from the ice.
KW - Cryoconcentration
KW - RSM
KW - centrifugation
KW - filter
KW - process parameters
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U2 - 10.1080/01496395.2018.1512615
DO - 10.1080/01496395.2018.1512615
M3 - Article
AN - SCOPUS:85055256396
VL - 54
SP - 786
EP - 794
JO - Separation Science and Technology
JF - Separation Science and Technology
SN - 0149-6395
IS - 5
ER -