@article{7ddd59350ff744c6b67635a105b767dd,
title = "Inactivation of Cryptosporidium parvum oocysts with ozone",
abstract = "Ozone inactivation rates for Cryptosporidium parvum (C. parvum) oocysts were determined with an in vitro excystation method based on excysted sporozoite counts. Results were consistent with published animal infectivity data for the same C. parvum strain. The inactivation kinetics for C. parvum were characterized by a lag phase followed by pseudo-first order kinetics. Both the magnitudes of the lag phase and the pseudo-first order rate constant were found to be different for C. parvum oocysts from two different sources, and to obey Arrhenius law for the experimental temperature range of 5-30°C. CT requirements for C. parvum inactivation were found to increase by an average factor of approximately three for every 10°C decrease in temperature.",
keywords = "C. parvum strains, Cryptosporidium parvum, In vitro excystation, Inactivation kinetics, Ozone disinfection, Semi-batch reactor, Temperature dependence",
author = "Rennecker, {Jason L.} and Mari{\~n}as, {Benito J.} and Owens, {James H.} and Rice, {Eugene W.}",
note = "Funding Information: The authors would like to thank Sharon A. Waller and Dr. Chung-Hsuang Hung for providing assistance and training during the early phases of this study, and Daniel B. Oerther for helping with the preparation of phase micrographs. The following individuals are also acknowledged for their advise and support: Dr Gerald L. McLaughlin, School of Medicine, Indiana University, Indianapolis; Dr Howard B. Gelberg, Dr Mark S. Kuhlenschmidt and Dr Julie K. Johnson, Veterinary Pathobiology, University of Illinois at Urbana-Champaign; Dr Allan J. Paul, Veterinary Parasitology, University of Illinois at Urbana-Champaign; Dr Steve J. Upton, Division of Biology, Kansas State University and Dr Henry H. Stibbs, Waterborne, Inc, New Orleans, LA. Experiments were performed at the William H. Richardson Memorial Disinfection Research Laboratory of the University of Illinois. This project was supported by a U.S. Environmental Protection Agency Environmental Technology Initiative Grant administered through Cooperative Agreement No. CR 824676-01. Copyright: Copyright 2020 Elsevier B.V., All rights reserved.",
year = "1999",
month = aug,
doi = "10.1016/S0043-1354(99)00116-5",
language = "English (US)",
volume = "33",
pages = "2481--2488",
journal = "Water Research",
issn = "0043-1354",
publisher = "Elsevier Limited",
number = "11",
}