Abstract
We present the first three-dimensional (3D) data sets recorded using optical coherence elastography (OCE). Uni-axial strain rate was measured on human skin in vivo using a spectral-domain optical coherence tomography (OCT) system providing >450 times higher line rate than previously reported for in vivo OCE imaging. Mechanical excitation was applied at a frequency of 125 Hz using a ring actuator sample arm with, for the first time in OCE measurements, a controlled static preload. We performed 3D-OCE, processed in 2D and displayed in 3D, on normal and hydrated skin and observed a more elastic response of the stratum corneum in the hydrated case.
Original language | English (US) |
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Pages (from-to) | 6623-6634 |
Number of pages | 12 |
Journal | Optics Express |
Volume | 19 |
Issue number | 7 |
DOIs | |
State | Published - Mar 28 2011 |
ASJC Scopus subject areas
- Atomic and Molecular Physics, and Optics