In vivo study of cross-sectional skeletal muscle fiber asymmetry with diffusion-weighted MRI

Dimitrios C. Karampinos, Kevin F. King, Brad P. Sutton, John G. Georgiadis

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Skeletal muscles are highly organized hierarchical structures characterized by an anisotropic arrangement of muscle fibers (myocytes) in fascicles. Due to its unique non-invasive microstructure probing capabilities, diffusion-weighted Magnetic Resonance Imaging (DW-MRI) constitutes a valuable non-invasive tool in the study of such fibrous biological tissues. We have implemented a DW-MRI sequence with highly sensitive directional encoding to quantify the microarchitectural properties of human calf muscles at rest. We have specifically focused on a composite model-based analysis of diffusion tensor MRI measurements to quantify in vivo the cross-sectional asymmetry of muscle fiber geometry, which is a microstructural feature well documented in prior histological studies.

Original languageEnglish (US)
Title of host publication29th Annual International Conference of IEEE-EMBS, Engineering in Medicine and Biology Society, EMBC'07
Pages327-330
Number of pages4
DOIs
StatePublished - Dec 1 2007
Event29th Annual International Conference of IEEE-EMBS, Engineering in Medicine and Biology Society, EMBC'07 - Lyon, France
Duration: Aug 23 2007Aug 26 2007

Publication series

NameAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
ISSN (Print)0589-1019

Other

Other29th Annual International Conference of IEEE-EMBS, Engineering in Medicine and Biology Society, EMBC'07
CountryFrance
CityLyon
Period8/23/078/26/07

ASJC Scopus subject areas

  • Signal Processing
  • Biomedical Engineering
  • Computer Vision and Pattern Recognition
  • Health Informatics

Fingerprint Dive into the research topics of 'In vivo study of cross-sectional skeletal muscle fiber asymmetry with diffusion-weighted MRI'. Together they form a unique fingerprint.

  • Cite this

    Karampinos, D. C., King, K. F., Sutton, B. P., & Georgiadis, J. G. (2007). In vivo study of cross-sectional skeletal muscle fiber asymmetry with diffusion-weighted MRI. In 29th Annual International Conference of IEEE-EMBS, Engineering in Medicine and Biology Society, EMBC'07 (pp. 327-330). [4352290] (Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings). https://doi.org/10.1109/IEMBS.2007.4352290