In vivo small animal lung speckle imaging with a benchtop in-line XPC system

A. B. Garson, S. Gunsten, S. Vasireddi, S. Brody, M. A. Anastasio

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

X-ray phase-contrast (XPC) images of mouse lungs were acquired in vivo with a benchtop XPC system employing a conventional microfocus source. A strong speckled intensity pattern was present in lung regions of the XPC radiographs, previously only observed in synchroton experiments and in situ benchtop studies. We showed how the texture characteristics of the speckle is influenced by the amount of air present in the lungs at different points in the breathing cycle.

Original languageEnglish (US)
Title of host publicationMedical Imaging 2016
Subtitle of host publicationPhysics of Medical Imaging
EditorsDespina Kontos, Joseph Y. Lo, Thomas G. Flohr
PublisherSPIE
ISBN (Electronic)9781510600188
DOIs
StatePublished - Jan 1 2016
Externally publishedYes
EventMedical Imaging 2016: Physics of Medical Imaging - San Diego, United States
Duration: Feb 28 2016Mar 2 2016

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume9783
ISSN (Print)1605-7422

Conference

ConferenceMedical Imaging 2016: Physics of Medical Imaging
Country/TerritoryUnited States
CitySan Diego
Period2/28/163/2/16

Keywords

  • in vivo
  • propagation based
  • small animal lung imaging
  • X-ray phase contrast

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

Fingerprint

Dive into the research topics of 'In vivo small animal lung speckle imaging with a benchtop in-line XPC system'. Together they form a unique fingerprint.

Cite this