In vivo measurement of the complex shear modulus of rat mammary tumors using shear wave imaging techniques

Yue Wang, Marko Orescanin, Michael F. Insana

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

This paper summarizes dynamic measurements of shear modulus constants acquired for spontaneously growing rat mammary tumors. Measurements are compared with histology to determine tumor types. We also report on 3D shear-wave velocity fields acquired from an inhomogeneous hydrogel phantom with known mechanical properties. Phantom measurements enable us to interpret the effects of tissue structure and geometry on viscoelastic parameter estimates, and demonstrate that reproducible measurements are possible in vivo. Viscoelastic properties describe the mechano-environment of cells undergoing malignant transformation and tumor growth.

Original languageEnglish (US)
Title of host publication2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10
PublisherIEEE Computer Society
Pages29-32
Number of pages4
ISBN (Print)9781424441235
DOIs
StatePublished - Jan 1 2010

Publication series

Name2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10

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ASJC Scopus subject areas

  • Biomedical Engineering

Cite this

Wang, Y., Orescanin, M., & Insana, M. F. (2010). In vivo measurement of the complex shear modulus of rat mammary tumors using shear wave imaging techniques. In 2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10 (pp. 29-32). [5626067] (2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10). IEEE Computer Society. https://doi.org/10.1109/IEMBS.2010.5626067