In vivo measurement of the complex shear modulus of rat mammary tumors using shear wave imaging techniques

Yue Wang, Marko Orescanin, Michael Insana

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

This paper summarizes dynamic measurements of shear modulus constants acquired for spontaneously growing rat mammary tumors. Measurements are compared with histology to determine tumor types. We also report on 3D shear-wave velocity fields acquired from an inhomogeneous hydrogel phantom with known mechanical properties. Phantom measurements enable us to interpret the effects of tissue structure and geometry on viscoelastic parameter estimates, and demonstrate that reproducible measurements are possible in vivo. Viscoelastic properties describe the mechano-environment of cells undergoing malignant transformation and tumor growth.

Original languageEnglish (US)
Title of host publication2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10
PublisherIEEE Computer Society
Pages29-32
Number of pages4
ISBN (Print)9781424441235
DOIs
StatePublished - Jan 1 2010

Publication series

Name2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10

Fingerprint

Shear waves
Rats
Tumors
Elastic moduli
Imaging techniques
Histology
Hydrogels
Tissue
Mechanical properties
Geometry

ASJC Scopus subject areas

  • Biomedical Engineering

Cite this

Wang, Y., Orescanin, M., & Insana, M. (2010). In vivo measurement of the complex shear modulus of rat mammary tumors using shear wave imaging techniques. In 2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10 (pp. 29-32). [5626067] (2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10). IEEE Computer Society. https://doi.org/10.1109/IEMBS.2010.5626067

In vivo measurement of the complex shear modulus of rat mammary tumors using shear wave imaging techniques. / Wang, Yue; Orescanin, Marko; Insana, Michael.

2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10. IEEE Computer Society, 2010. p. 29-32 5626067 (2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Wang, Y, Orescanin, M & Insana, M 2010, In vivo measurement of the complex shear modulus of rat mammary tumors using shear wave imaging techniques. in 2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10., 5626067, 2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10, IEEE Computer Society, pp. 29-32. https://doi.org/10.1109/IEMBS.2010.5626067
Wang Y, Orescanin M, Insana M. In vivo measurement of the complex shear modulus of rat mammary tumors using shear wave imaging techniques. In 2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10. IEEE Computer Society. 2010. p. 29-32. 5626067. (2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10). https://doi.org/10.1109/IEMBS.2010.5626067
Wang, Yue ; Orescanin, Marko ; Insana, Michael. / In vivo measurement of the complex shear modulus of rat mammary tumors using shear wave imaging techniques. 2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10. IEEE Computer Society, 2010. pp. 29-32 (2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10).
@inproceedings{b7522520ff0b4f0a8b3e738b3935e5a8,
title = "In vivo measurement of the complex shear modulus of rat mammary tumors using shear wave imaging techniques",
abstract = "This paper summarizes dynamic measurements of shear modulus constants acquired for spontaneously growing rat mammary tumors. Measurements are compared with histology to determine tumor types. We also report on 3D shear-wave velocity fields acquired from an inhomogeneous hydrogel phantom with known mechanical properties. Phantom measurements enable us to interpret the effects of tissue structure and geometry on viscoelastic parameter estimates, and demonstrate that reproducible measurements are possible in vivo. Viscoelastic properties describe the mechano-environment of cells undergoing malignant transformation and tumor growth.",
author = "Yue Wang and Marko Orescanin and Michael Insana",
year = "2010",
month = "1",
day = "1",
doi = "10.1109/IEMBS.2010.5626067",
language = "English (US)",
isbn = "9781424441235",
series = "2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10",
publisher = "IEEE Computer Society",
pages = "29--32",
booktitle = "2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10",

}

TY - GEN

T1 - In vivo measurement of the complex shear modulus of rat mammary tumors using shear wave imaging techniques

AU - Wang, Yue

AU - Orescanin, Marko

AU - Insana, Michael

PY - 2010/1/1

Y1 - 2010/1/1

N2 - This paper summarizes dynamic measurements of shear modulus constants acquired for spontaneously growing rat mammary tumors. Measurements are compared with histology to determine tumor types. We also report on 3D shear-wave velocity fields acquired from an inhomogeneous hydrogel phantom with known mechanical properties. Phantom measurements enable us to interpret the effects of tissue structure and geometry on viscoelastic parameter estimates, and demonstrate that reproducible measurements are possible in vivo. Viscoelastic properties describe the mechano-environment of cells undergoing malignant transformation and tumor growth.

AB - This paper summarizes dynamic measurements of shear modulus constants acquired for spontaneously growing rat mammary tumors. Measurements are compared with histology to determine tumor types. We also report on 3D shear-wave velocity fields acquired from an inhomogeneous hydrogel phantom with known mechanical properties. Phantom measurements enable us to interpret the effects of tissue structure and geometry on viscoelastic parameter estimates, and demonstrate that reproducible measurements are possible in vivo. Viscoelastic properties describe the mechano-environment of cells undergoing malignant transformation and tumor growth.

UR - http://www.scopus.com/inward/record.url?scp=78650818022&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=78650818022&partnerID=8YFLogxK

U2 - 10.1109/IEMBS.2010.5626067

DO - 10.1109/IEMBS.2010.5626067

M3 - Conference contribution

C2 - 21095637

AN - SCOPUS:78650818022

SN - 9781424441235

T3 - 2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10

SP - 29

EP - 32

BT - 2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10

PB - IEEE Computer Society

ER -