In vivo flow-independent T2 measurements of superior mesenteric vein blood in diagnosis of chronic mesenteric ischemia: A preliminary evaluation

K. C.P. Li, R. L. Dalman, G. A. Wright

Research output: Contribution to journalArticlepeer-review

Abstract

Rationale and Objectives. The authors attempted to determine whether the T2 relaxation time of superior mesenteric vein (SMV) blood would decrease in patients with chronic mesenteric ischemia after a meal. Materials and Methods. Thirty-two patients without chronic mesenteric ischemia and eight patients with symptomatic chronic mesenteric ischemia underwent magnetic resonance (MR) imaging. All examinations were performed with a 1.5-T unit, a modified Carr-Purcell-Meiboom-Gill sequence, final section-selective pulse of 180°, and spiral readout gradients. Measurements of SMV blood T2 were obtained after at least 6 hours of fasting and 15 and 35 minutes after ingestion of 240 mL of a liquid nutritional supplement. Maximal change of the SMV blood T2 was expressed as a percentage of the fasting T2 in all patients. Results. In control patients, SMV blood T2 increased postprandially by 9.4% ± 1.3 (95% confidence level; range, 6.8%-11.9%) (data range, -7.3% to 25.6%) compared with fasting T2. In symptomatic patients, SMV blood T2 decreased postprandially by 15.8% ± 2.2 (95% confidence level; range, -20.1% to -10.7%) (data range, -7.9% to -25.3%). The difference between the two groups was statistically significant (P < .0001 by Student unpaired t test). Conclusion. Measurement of SMV blood T2 is a promising test for chronic mesenteric ischemia diagnosis. Therefore, conversion of T2 measurements to estimate oxygen saturation may not be necessary for all cases of this clinical indication.

Original languageEnglish (US)
Pages (from-to)530-534
Number of pages5
JournalAcademic Radiology
Volume6
Issue number9
DOIs
StatePublished - 1999
Externally publishedYes

Keywords

  • Ischemia
  • Magnetic resonance (MR)
  • Mesentery
  • Vascular studies

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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