In vivo and in vitro MR imaging of renal tumors: Histopathologic correlation and pulse sequence optimization

L. E. Quint, G. M. Glazer, T. L. Chenevert, K. P. Fechner, P. W. Gikas, P. K. Shireman, H. B. Grossman, K. C. Li

Research output: Contribution to journalArticle

Abstract

Magnetic resonance (MR) imaging has given mixed results in the detection of renal masses. To identify the reasons for this and to determine the optimal pulse sequences for evaluating renal tumors, the authors imaged 12 primary renal tumors in vivo and 17 in vitro at 0.35 T. Histopathologic findings for each specimen were closely correlated with the MR images. Four of seven solid tumors imaged in vivo were isointense with surrounding normal renal parenchyma at all pulse sequences. The other three tumors were hyperintense in vivo at T2-weighted sequences. At heavily T2-weighted sequences eight solid tumors were hyperintense in vitro and four were hypointense. There was no correlation between signal intensity and specific tissue type or histologic pattern for solid tumors. The five cystic tumors were well seen both in vivo and in vitro on T2-weighted images. However, the signal intensity of the cyst fluid was an unreliable indicator of benignancy. SE MR imaging at 0.35 T has significant limitations in the detection of solid renal masses.

Original languageEnglish (US)
Pages (from-to)359-362
Number of pages4
JournalRadiology
Volume169
Issue number2
DOIs
StatePublished - Jan 1 1988
Externally publishedYes

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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    Quint, L. E., Glazer, G. M., Chenevert, T. L., Fechner, K. P., Gikas, P. W., Shireman, P. K., Grossman, H. B., & Li, K. C. (1988). In vivo and in vitro MR imaging of renal tumors: Histopathologic correlation and pulse sequence optimization. Radiology, 169(2), 359-362. https://doi.org/10.1148/radiology.169.2.3174983