This study presents a multi-walled poly(ethylene glycol) diacrylate hydrogel tube formed by the simple self-folding of a bi-layered hydrogel patch. The gel tube has the capability to release encapsulated molecules through designated pathways in a sustained manner. Therefore, the gel tube encapsulating the vascular endothelial growth factor significantly increases the vascular densities and vessel diameters at an implantation site.

Original languageEnglish (US)
Pages (from-to)5568-5573
Number of pages6
JournalAdvanced Materials
Issue number39
StatePublished - Oct 18 2013


  • angiogenesis
  • drug delivery
  • expansion ratio
  • neovascularization
  • self-folding

ASJC Scopus subject areas

  • General Materials Science
  • Mechanics of Materials
  • Mechanical Engineering


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