Improving limited-view reconstruction in photoacoustic tomography by incorporating a priori boundary information

Mark A. Anastasio, Kun Wang, Jin Zhang, Gabe A. Kruger, Daniel Reinecke, Robert A. Kruger

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Photoacoustic tomography (PAT) is an emerging ultrasound-mediated biophotonic imaging modality that has great potential for many biomedical imaging applications. In many practical implementations of PAT, the photoacoustic signals are recorded over an aperture that does not enclose the object, which results in a limitedview tomographic reconstruction problem. When conventional reconstruction algorithms are applied to limitedview measurement data, the resulting images can contain severe image artifacts and distortions. To circumvent such artifacts, we exploit a priori information about the locations of boundaries within the object (optical absorption function) to improve the fidelity of the reconstructed images. Such boundary information can be inferred, for example, from a co-registered B-mode ultrasound image or other adjunct imaging study. We develop and implement an iterative reconstruction algorithm that exploits a priori object information in the form of support constraints. We demonstrate that the developed iterative reconstruction algorithm produces images with reduced artifact levels as compared to those produced by a conventional PAT reconstruction algorithm.

Original languageEnglish (US)
Title of host publicationPhotons Plus Ultrasound
Subtitle of host publicationImaging and Sensing 2008: The Ninth Conference on Biomedical Thermoacoustics, Optoacoustics, and Acousto-optics
DOIs
StatePublished - Apr 23 2008
Externally publishedYes
Event9th Conference on Photons Plus Ultrasound: Imaging and Sensing 2008 - San Jose, CA, United States
Duration: Jan 20 2008Jan 23 2008

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume6856
ISSN (Print)1605-7422

Conference

Conference9th Conference on Photons Plus Ultrasound: Imaging and Sensing 2008
CountryUnited States
CitySan Jose, CA
Period1/20/081/23/08

Keywords

  • Limited-view tomography
  • Photoacoustic tomography

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

Fingerprint Dive into the research topics of 'Improving limited-view reconstruction in photoacoustic tomography by incorporating a priori boundary information'. Together they form a unique fingerprint.

  • Cite this

    Anastasio, M. A., Wang, K., Zhang, J., Kruger, G. A., Reinecke, D., & Kruger, R. A. (2008). Improving limited-view reconstruction in photoacoustic tomography by incorporating a priori boundary information. In Photons Plus Ultrasound: Imaging and Sensing 2008: The Ninth Conference on Biomedical Thermoacoustics, Optoacoustics, and Acousto-optics [68561B] (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 6856). https://doi.org/10.1117/12.764178