Implications of depression in rheumatoid arthritis: Do subtypes really matter?

Karen L. Smarr, Jerry C. Parker, John F. Kosciulek, Janda L. Buchholz, Karen D. Multon, John E. Hewett, Geetha R. Komatireddy

Research output: Contribution to journalArticle

Abstract

Objective. To examine depressive disorders and health status in patients with rheumatoid arthritis (RA), controlling for potential confounds. Method. Subjects (n = 426) completed measures of depressive symptoms (Center for Epidemiological Studies Depression Scale [CES-D]) and health status (Arthritis Impact Measurement Scales 2 [AIMS2]), via cross-sectional survey. Subjects (n = 299) with few depressive symptoms (CES-D ≤10) were not evaluated further. Subjects with CES-D ≥11 were interviewed using the Primary Care Evaluation of Mental Disorders to diagnose major depressive disorder (MDD; n = 46), dysthymic disorder (DD; n = 21), or minor depressive disorder (MND; n = 18). Results. Regression analyses examined differences between the depressive disorders on AIMS2 subscales. Health status scores were similar between the depressive disorder subcategories; significant differences were found between MDD and MND on AIMS2 Physical scores and MDD and DD on AIMS2 Symptom scores. Conclusion. Regarding health status, presence of depression itself seems to overshadow differences between depression subtypes; antidepressant treatments/referrals for persons with concomitant RA and any depressive disorder subtype appear warranted.

Original languageEnglish (US)
Pages (from-to)23-32
Number of pages10
JournalArthritis Care and Research
Volume13
Issue number1
StatePublished - Oct 21 2000
Externally publishedYes

Keywords

  • Depressive disorders
  • Health status
  • Rheumutoid arthritis

ASJC Scopus subject areas

  • Rheumatology

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  • Cite this

    Smarr, K. L., Parker, J. C., Kosciulek, J. F., Buchholz, J. L., Multon, K. D., Hewett, J. E., & Komatireddy, G. R. (2000). Implications of depression in rheumatoid arthritis: Do subtypes really matter? Arthritis Care and Research, 13(1), 23-32.