Impact of distal mutation on hydrogen transfer interface and substrate conformation in soybean lipoxygenase

Keyphrases

• Hydrogen Transfer 100%
• Soybean Lipoxygenase 100%
• Distal mutation 100%
• Substrate Conformation 100%
• Active Sites 66%
• Temperature Effect 66%
• Kinetic Isotope Effect 66%
• Linoleic Acid 66%
• Equilibrium Distance 66%
• Soybean lipoxygenase-1 66%
• Molecular Dynamics Simulation 33%
• All-atom Molecular Dynamics Simulation 33%
• Donor-acceptor 33%
• Solvate 33%
• Leucine 33%
• Interface Properties 33%
• Electron Transfer Mechanism 33%
• Proton-coupled Electron Transfer 33%
• Catalytic Rate 33%
• Proton Donor 33%
• Frequency Reduction 33%
• Non-adiabatic 33%
• Mutant Enzyme 33%
• Hydrogen Abstraction Reaction 33%
• Proton Transfer Equilibrium 33%
• Mutation Impact 33%

Biochemistry, Genetics and Molecular Biology

• Conformation 100%
• Hydrogen Transfer 100%
• Lipoxygenase 100%
• Dynamics 66%
• Active Site 66%
• Enzyme 66%
• Kinetic Isotope Effect 66%
• Temperature Dependence 66%
• Linoleic Acid 66%
• Proton Transport 33%
• Electron Transport 33%
• Wild Type 33%
• Isoleucine 33%